An Investigation into the Usage of Monosaccharides with GLUT1 and GLUT3 as Prognostic Indicators for Cancer.

The monosaccharides, glucose, fructose and galactose, are the most common and simplest forms of carbohydrates. The aim of this study was to determine the uptake of glucose as a potential therapeutic target agent for cancer treatment. The stability and transportation calculations of the monosaccharid...

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Publicado en:Nutrition & Cancer Vol. 74; no. 2; pp. 515 - 520
Autor principal: Gökalp, Faik
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2022
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/01635581.2021.1895233
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        atl: An Investigation into the Usage of Monosaccharides with GLUT1 and GLUT3 as Prognostic Indicators for Cancer.
      aug:
        au: Gökalp, Faik
        affil: Faculty of Education, Department of Maths and Science Education, Science Education, Kırıkkale University, Yahşihan/Kırıkkale, Turkey
      sug:
        subj:
          Neoplasms Therapy
          Monosaccharides Therapeutic Use
          Carrier Proteins Metabolism
          Biological Markers
          Human
          Stability
          Nuclear Physics
      ab: The monosaccharides, glucose, fructose and galactose, are the most common and simplest forms of carbohydrates. The aim of this study was to determine the uptake of glucose as a potential therapeutic target agent for cancer treatment. The stability and transportation calculations of the monosaccharides were carried out in the blood phase by using the density functional theory and docking. The reactivity of monosaccharides, disaccharides and their transportation with GLUT1 and GLUT3 as prognostic indicators for cancer were investigated. The theoretical results of this study were supported by those reported in the literature and used in the prediction of the mechanisms of monosaccharides and the interpretation of their reactivities.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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