Advanced neuroimaging techniques in epilepsy.
Purpose Of Review: We review significant advances in epilepsy imaging in recent years.Recent Findings: Structural MRI at 7T with optimization of acquisition and postacquisition image processing increases the diagnostic yield but artefactual findings remain a challenge. MRI analysis from multiple sit...
| Publicado en: | Current Opinion in Neurology Vol. 35; no. 2; pp. 189 - 196 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Apr2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155530073&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 155530073 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13507540 IM9 jtl: Current Opinion in Neurology issn: 13507540 maglogo: N pubinfo: dt: Apr2022 vid: 35 iid: 2 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 155530073 155530073 NLM34812749 155530073 10.1097/WCO.0000000000001007 NLM34812749 155530073 ppf: 189 ppct: 7 formats: tig: atl: Advanced neuroimaging techniques in epilepsy. aug: au: Duncan, John S. Trimmel, Karin sug: subj: Epilepsy Epilepsy, Temporal Lobe Surgery Epilepsy Surgery Magnetic Resonance Imaging Methods Tomography, Emission-Computed Seizures Human Neuroradiography Methods Comparative Studies Multicenter Studies Evaluation Research Funding Source ab: Purpose Of Review: We review significant advances in epilepsy imaging in recent years.Recent Findings: Structural MRI at 7T with optimization of acquisition and postacquisition image processing increases the diagnostic yield but artefactual findings remain a challenge. MRI analysis from multiple sites indicates different atrophy patterns and white matter diffusion abnormalities in temporal lobe and generalized epilepsies, with greater abnormalities close to the presumed seizure source. Structural and functional connectivity relate to seizure spread and generalization; longitudinal studies are needed to clarify the causal relationship of these associations. Diffusion MRI may help predict surgical outcome and network abnormalities extending beyond the epileptogenic zone. Three-dimensional multimodal imaging can increase the precision of epilepsy surgery, improve seizure outcome and reduce complications. Language and memory fMRI are useful predictors of postoperative deficits, and lead to risk minimization. FDG PET is useful for clinical studies and specific ligands probe the pathophysiology of neurochemical fluxes and receptor abnormalities.Summary: Improved structural MRI increases detection of abnormalities that may underlie epilepsy. Diffusion, structural and functional MRI indicate the widespread associations of epilepsy syndromes. These can assist stratification of surgical outcome and minimize risk. PET has continued utility clinically and for research into the pathophysiology of epilepsies. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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