Behavioral response bias and event‐related brain potentials implicate elevated incentive salience attribution to alcohol cues in emerging adults with lower sensitivity to alcohol.
Aims: This study used a behavioral approach‐avoidance task including images of alcoholic beverages to test whether low sensitivity to alcohol (LS) is a phenotypical marker of a dispositional propensity to attribute bottom‐up incentive value to naturally conditioned alcohol cues. Design, setting and...
| Publicado en: | Addiction Vol. 117; no. 4; pp. 892 - 905 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Apr2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155656571&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 155656571 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Apr2022 vid: 117 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 155656571 153512018 155656571 155656571 10.1111/add.15728 155656571 ppf: 892 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Behavioral response bias and event‐related brain potentials implicate elevated incentive salience attribution to alcohol cues in emerging adults with lower sensitivity to alcohol. aug: au: Cofresí, Roberto U. Kohen, Casey B. Motschman, Courtney A. Wiers, Reinout W. Piasecki, Thomas M. Bartholow, Bruce D. affil: Department of Psychological Sciences, University of Missouri, Columbia MO,, USA sug: subj: Evoked Potentials In Adulthood Behavior Alcohol Abuse Human Young Adult Experimental Studies Missouri Sensitivity and Specificity Electroencephalography Linear Regression Multimethod Studies Descriptive Statistics Conflict (Psychology) Large-Scale Brain Networks Sign Test ab: Aims: This study used a behavioral approach‐avoidance task including images of alcoholic beverages to test whether low sensitivity to alcohol (LS) is a phenotypical marker of a dispositional propensity to attribute bottom‐up incentive value to naturally conditioned alcohol cues. Design, setting and participants: Experimental study with a measured individual difference variable at a university psychology laboratory in Missouri, MO, USA. Participants were 178 emerging adults (aged 18–20 years) varying in self‐reported sensitivity to alcohol's acute effects. Measurements Participants completed the alcohol approach‐avoidance task while behavior (response time; RT) and the electroencephalogram (EEG) were recorded. Stimulus‐locked event‐related potentials (ERPs) provided indices of integrated (top‐down and bottom‐up) stimulus incentive value (P3 amplitude) and conflict between top‐down task demands and bottom‐up response propensities (N450 amplitude). Findings Linear mixed models showed faster RT for 'alcohol‐approach' relative to 'alcohol‐avoid' trials for lower‐sensitivity (LS) [meanD ± standard errorD (MD ± SED) = 29.51 ± 9.74 ms, t(328) = 3.03, P = 0.003] but not higher‐sensitivity (HS) individuals (MD ± SED = 2.27 ± 9.33 ms, t(328) = 0.243, P = 0.808). There was enhanced N450 amplitude (response conflict) for alcohol‐avoid relative to alcohol‐approach trials for LS participants (MD ± SED = 0.811 ± 0.198 μV, Z = 4.108, P < 0.001) and enhanced N450 amplitude for alcohol‐approach relative to alcohol‐avoid for HS participants (MD ± SED = 0.419 ± 0.188 μV, Z = 2.235, P = 0.025). There was also enhanced P3 amplitude for alcohol‐approach relative to alcohol‐avoid for LS (MD ± SED = 0.825 ± 0.204 μV, Z = 4.045, P < 0.001) but not HS (MD ± SED = 0.013 ± 0.194 μV, Z = 0.068, P = 0.946). Conclusions: Findings from a human laboratory study appear to support the notion that low sensitivity to alcohol indexes a propensity to attribute bottom–up incentive value to naturally conditioned alcohol cues. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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