Are incisional biopsies reliable for selecting definitive treatment of ameloblastomas? A 15-year interdisciplinary retrospective study.
Objectives: Sampling error in incisional biopsy can lead to under/overtreatment. The aim of this study is to determine the incidence of sampling error/discordance between incisional biopsy and final diagnosis and consequences for treatment outcomes.Study Design: This study is a retrospective cohort...
| Publicado en: | Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology Vol. 133; no. 4; pp. 388 - 396 |
|---|---|
| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Apr2022
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155693798&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 155693798 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 22124403 ETSG jtl: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology issn: 22124403 maglogo: N pubinfo: dt: Apr2022 vid: 133 iid: 4 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 155693798 155693798 NLM34511343 155693798 10.1016/j.oooo.2021.07.008 NLM34511343 155693798 ppf: 388 ppct: 8 formats: tig: atl: Are incisional biopsies reliable for selecting definitive treatment of ameloblastomas? A 15-year interdisciplinary retrospective study. aug: au: Renapurkar, Shravan Kumar Broccoli, Peter Carrico, Caroline Glass, Sarah affil: Assistant Professor, Associate Program Director, Department of Oral and Maxillofacial Surgery, Virginia Commonwealth University, Richmond, VA, USA sug: subj: Ameloblastoma Surgery Ameloblastoma Pathology Female Male Treatment Outcomes Retrospective Design Biopsy Methods Scales Funding Source Female Male ab: Objectives: Sampling error in incisional biopsy can lead to under/overtreatment. The aim of this study is to determine the incidence of sampling error/discordance between incisional biopsy and final diagnosis and consequences for treatment outcomes.Study Design: This study is a retrospective cohort study of patients treated for ameloblastoma at an academic medical center from 2005 to 2020. Patients with minimum of 1 year of follow-up after definitive treatment and complete documentation were included. Clinical variables included radiographic findings, incisional biopsy, and final histopathology. Outcome variables were discordance between incisional biopsy and final pathology as well as recurrence rates. Results are primarily descriptive. Fisher's exact test was used to test for differences in recurrence rates.Results: Twenty-three patients (14 male/9 female) met the inclusion criteria. Overall, discordance was found in 2 cases (8.6%) and sampling error in 3 (13.04%). One of the 3 cases showing sampling error had recurrence and required secondary resection. Six patients (26.1%) had recurrent lesions, and all patients underwent enucleation and curettage with or without peripheral ostectomy.Conclusions: Incisional biopsies by themselves are not always consistent with a final diagnosis. Possibility of sampling error should be included in informed consent. Consultation with an oral pathologist is essential at initial and final histopathologic evaluation. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|