Hybrid Convolution Neural Network in Classification of Cancer in Histopathology Images.

Cancer statistics in 2020 reveals that breast cancer is the most common form of cancer among women in India. One in 28 women is likely to develop breast cancer during their lifetime. The mortality rate is 1.6 to 1.7 times higher than maternal mortality rates. According to the US statistics, about 42...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Digital Imaging Vol. 35; no. 2; pp. 248 - 258
Autor principal: Angayarkanni, S. Pitchumani
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Apr2022
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155757664&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 155757664
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        08971889
        DOQ
      jtl: Journal of Digital Imaging
      issn: 08971889
      maglogo: N
    pubinfo:
      dt: Apr2022
      vid: 35
      iid: 2
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        155757664
        154633629
        155757664
        155757664
        10.1007/s10278-021-00541-3
        155757664
      ppf: 248
      ppct: 10
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Hybrid Convolution Neural Network in Classification of Cancer in Histopathology Images.
      aug:
        au: Angayarkanni, S. Pitchumani
        affil: Sri Ramachandra Faculty of Engineering and Technology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, India
      sug:
        subj:
          Neural Networks (Computer)
          Neoplasms Classification
          Diagnostic Imaging Methods
          Early Detection of Cancer Methods
          Human
          Image Processing, Computer Assisted
          Descriptive Statistics
          Female
          India
          Deep Learning
          Bioinformatics
          Female
      ab: Cancer statistics in 2020 reveals that breast cancer is the most common form of cancer among women in India. One in 28 women is likely to develop breast cancer during their lifetime. The mortality rate is 1.6 to 1.7 times higher than maternal mortality rates. According to the US statistics, about 42,170 women in the US are expected to die in 2020 from breast cancer. The chance of survival can be increased through early and accurate diagnosis of cancer. The pathologists manually analyze the histopathology images using high-resolution microscopes to detect the mitotic cells. This is a time-consuming process because there is a minute difference between the normal and mitotic cells. To overcome these challenges, an automatic analysis and detection of breast cancer by using histopathology images play a vital role in prognosis. Earlier researchers used conventional image processing techniques for the detection of mitotic cells. These methods were found to be producing results with low accuracy and time-consuming. Therefore, several deep learning techniques were adopted by researchers to increase the accuracy and minimize the time. The hybrid deep learning model is proposed for selecting abstract features from the histopathology images. In the proposed approach, we have concatenated two different CNN architectures into a single model for effective classification of mitotic cells. Convolution neural network (CNN) automatically detects efficient features without human intervention and classifies cancerous and non-cancerous images using a hybrid fully connected network. It is a computationally efficient, very powerful, and efficient model for performing automatic feature extraction. It detects different phenotypic signatures of nuclei. In order to enhance the accuracy and computational efficiency, the histopathology images are preprocessed, segmented, and feature extracted through CNN and fed into a hybrid CNN for classification. The hybrid CNN is obtained by concatenating two CNN models; together, this is called model leveraging. Model averaging can be improved by weighting the contributions of each sub-model to the combined prediction by the expected performance of the sub-model. The proposed hybrid CNN architecture with data preprocessing with median filter and Otsu-based segmentation technique is trained using 50,000 images and tested using 50,000 images. It provides an overall accuracy of 98.9%.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N