Detection and Grading of Hypertensive Retinopathy Using Vessels Tortuosity and Arteriovenous Ratio.

Hypertensive retinopathy (HR) refers to changes in the morphological diameter of the retinal vessels due to persistent high blood pressure. Early detection of such changes helps in preventing blindness or even death due to stroke. These changes can be quantified by computing the arteriovenous ratio...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 2; pp. 281 - 302
Autores principales: Badawi, Sufian A., Fraz, Muhammad Moazam, Shehzad, Muhammad, Mahmood, Imran, Javed, Sajid, Mosalam, Emad, Nileshwar, Ajay Kamath
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Springer Nature
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          Badawi, Sufian A.
          Fraz, Muhammad Moazam
          Shehzad, Muhammad
          Mahmood, Imran
          Javed, Sajid
          Mosalam, Emad
          Nileshwar, Ajay Kamath
        affil: School of Electrical Engineering and Computer Science, National University of Sciences and Technology (NUST), Islamabad, Pakistan
      sug:
        subj:
          Hypertension Diagnosis
          Retinal Diseases Diagnosis
          Retinal Vein Analysis
          Retinal Artery Analysis
          Severity of Illness Evaluation
          Diagnosis, Computer Assisted
          Decision Support Systems, Clinical
          Human
          Automation
          Intraocular Pressure
          Descriptive Statistics
          Image Interpretation, Computer Assisted
          Image Processing, Computer Assisted
      ab: Hypertensive retinopathy (HR) refers to changes in the morphological diameter of the retinal vessels due to persistent high blood pressure. Early detection of such changes helps in preventing blindness or even death due to stroke. These changes can be quantified by computing the arteriovenous ratio and the tortuosity severity in the retinal vasculature. This paper presents a decision support system for detecting and grading HR using morphometric analysis of retinal vasculature, particularly measuring the arteriovenous ratio (AVR) and retinal vessel tortuosity. In the first step, the retinal blood vessels are segmented and classified as arteries and veins. Then, the width of arteries and veins is measured within the region of interest around the optic disk. Next, a new iterative method is proposed to compute the AVR from the caliber measurements of arteries and veins using Parr–Hubbard and Knudtson methods. Moreover, the retinal vessel tortuosity severity index is computed for each image using 14 tortuosity severity metrics. In the end, a hybrid decision support system is proposed for the detection and grading of HR using AVR and tortuosity severity index. Furthermore, we present a new publicly available retinal vessel morphometry (RVM) dataset to evaluate the proposed methodology. The RVM dataset contains 504 retinal images with pixel-level annotations for vessel segmentation, artery/vein classification, and optic disk localization. The image-level labels for vessel tortuosity index and HR grade are also available. The proposed methods of iterative AVR measurement, tortuosity index, and HR grading are evaluated using the new RVM dataset. The results indicate that the proposed method gives superior performance than existing methods. The presented methodology is a novel advancement in automated detection and grading of HR, which can potentially be used as a clinical decision support system.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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