Unsupervised Deep Anomaly Detection for Medical Images Using an Improved Adversarial Autoencoder.

Anomaly detection has been applied in the various disease of medical practice, such as breast cancer, retinal, lung lesion, and skin disease. However, in real-world anomaly detection, there exist a large number of healthy samples, and but very few sick samples. To alleviate the problem of data imbal...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 2; pp. 153 - 162
Autores principales: Zhang, Haibo, Guo, Wenping, Zhang, Shiqing, Lu, Hongsheng, Zhao, Xiaoming
Formato: equations & formulas pictorial tables/charts Journal Article
Publicado: Springer Nature Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Springer Nature
      place: New York, New York
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        atl: Unsupervised Deep Anomaly Detection for Medical Images Using an Improved Adversarial Autoencoder.
      aug:
        au:
          Zhang, Haibo
          Guo, Wenping
          Zhang, Shiqing
          Lu, Hongsheng
          Zhao, Xiaoming
        affil: Taizhou Central Hospital (Taizhou University Hospital), Taizhou University, 318000, Zhejiang, China
      sug:
        subj:
          Diagnostic Imaging
          Image Enhancement
          Radiography Methods
          Abnormalities Diagnosis
          Autoencoder
          Semantics
          Minimum Data Set
      ab: Anomaly detection has been applied in the various disease of medical practice, such as breast cancer, retinal, lung lesion, and skin disease. However, in real-world anomaly detection, there exist a large number of healthy samples, and but very few sick samples. To alleviate the problem of data imbalance in anomaly detection, this paper proposes an unsupervised learning method for deep anomaly detection based on an improved adversarial autoencoder, in which a module called chain of convolutional block (CCB) is employed instead of the conventional skip-connections used in adversarial autoencoder. Such CCB connections provide considerable advantages via direct connections, not only preserving both global and local information but also alleviating the problem of semantic disparity between the encoding features and the corresponding decoding features. The proposed method is thus able to capture the distribution of normal samples within both image space and latent vector space. By means of minimizing the reconstruction error within both spaces during training phase, higher reconstruction error during test phase is indicative of an anomaly. Our method is trained only on the healthy persons in order to learn the distribution of normal samples and can detect sick samples based on high deviation from the distribution of normality in an unsupervised way. Experimental results for multiple datasets from different fields demonstrate that the proposed method yields superior performance to state-of-the-art methods.
      pubtype: Academic Journal
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        equations & formulas
        pictorial
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    language: English
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