Antibiotic prophylaxis for traumatic facial fractures.

What is known and objective: The purpose of this paper is to discuss the limitations of the evidence supporting the SIS recommendations for antibiotic prescribing in patients with traumatic facial fractures and to provide suggestions for clinical decision‐making and further research in this area giv...

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Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 47; no. 3; pp. 386 - 396
Autores principales: Erstad, Brian L., Kopp, Brian J., Tang, Andrew L.
Formato: Journal Article
Publicado: Wiley-Blackwell Mar2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2022
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      pub: Wiley-Blackwell
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        atl: Antibiotic prophylaxis for traumatic facial fractures.
      aug:
        au:
          Erstad, Brian L.
          Kopp, Brian J.
          Tang, Andrew L.
        affil: Department of Pharmacy Practice and Science, University of Arizona, Tucson AZ,, USA
      sug:
        subj:
          Antibiotic Prophylaxis
          Skull Fractures Surgery
          Emergency Patients
          Decision Making, Clinical
          Prescribing Patterns
          Surgical Wound Infection Prevention and Control
          Mandibular Fractures Surgery
          United States
          United Kingdom
          Practice Guidelines
          Treatment Outcomes
          Patient Safety
      ab: What is known and objective: The purpose of this paper is to discuss the limitations of the evidence supporting the SIS recommendations for antibiotic prescribing in patients with traumatic facial fractures and to provide suggestions for clinical decision‐making and further research in this area given the wide variation in prescribing practices. Comment: The Surgical Infection Society (SIS) recently published guidelines on antibiotic use in patients with traumatic facial fractures. The guidelines recommend against the use of prophylactic antibiotics for all adult patients with mandibular or non‐mandibular facial fractures undergoing non‐operative or operative procedures. Despite the available evidence, surveys conducted in the United States and the United Kingdom prior to the publication of the SIS guidelines demonstrate substantial preoperative, intraoperative and postoperative prophylactic prescribing of antibiotics for patients with facial fractures undergoing surgery. What is new and conclusion: With the exception of strong recommendations based on moderate‐quality evidence to avoid prolonged postoperative antibiotic prophylaxis, the weak recommendations in the guidelines are a function of low‐quality evidence. A logical choice for a narrow‐spectrum antibiotic is cefazolin administered within 1 h of surgery and no longer than 24 h after surgery, since it is the gold standard of comparison based on clinical practice guidelines concerning antibiotic prophylaxis.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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