An atomic approach to the design and implementation of a research data warehouse.
Objective: As a long-standing Clinical and Translational Science Awards (CTSA) Program hub, the University of Pittsburgh and the University of Pittsburgh Medical Center (UPMC) developed and implemented a modern research data warehouse (RDW) to efficiently provision electronic patient data for clinic...
| Publicado en: | Journal of the American Medical Informatics Association Vol. 29; no. 4; pp. 601 - 609 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
Apr2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155812588&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 155812588 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10675027 FZ9 jtl: Journal of the American Medical Informatics Association issn: 10675027 maglogo: N pubinfo: dt: Apr2022 vid: 29 iid: 4 pid: 622 pub: Oxford University Press / USA artinfo: ui: 155812588 155812588 NLM34613409 155812588 10.1093/jamia/ocab204 NLM34613409 155812588 ppf: 601 ppct: 8 formats: tig: atl: An atomic approach to the design and implementation of a research data warehouse. aug: au: Visweswaran, Shyam McLay, Brian Cappella, Nickie Morris, Michele Milnes, John T Reis, Steven E Silverstein, Jonathan C Becich, Michael J affil: Department of Biomedical Informatics, University of Pittsburgh , Pittsburgh, Pennsylvania, USA sug: subj: Health Insurance Portability and Accountability Act United States Institutional Review Information Retrieval Human Comparative Studies Multicenter Studies Evaluation Research Validation Studies Scales ab: Objective: As a long-standing Clinical and Translational Science Awards (CTSA) Program hub, the University of Pittsburgh and the University of Pittsburgh Medical Center (UPMC) developed and implemented a modern research data warehouse (RDW) to efficiently provision electronic patient data for clinical and translational research.Materials and Methods: We designed and implemented an RDW named Neptune to serve the specific needs of our CTSA. Neptune uses an atomic design where data are stored at a high level of granularity as represented in source systems. Neptune contains robust patient identity management tailored for research; integrates patient data from multiple sources, including electronic health records (EHRs), health plans, and research studies; and includes knowledge for mapping to standard terminologies.Results: Neptune contains data for more than 5 million patients longitudinally organized as Health Insurance Portability and Accountability Act (HIPAA) Limited Data with dates and includes structured EHR data, clinical documents, health insurance claims, and research data. Neptune is used as a source for patient data for hundreds of institutional review board-approved research projects by local investigators and for national projects.Discussion: The design of Neptune was heavily influenced by the large size of UPMC, the varied data sources, and the rich partnership between the University and the healthcare system. It includes several unique aspects, including the physical warehouse straddling the University and UPMC networks and management under an HIPAA Business Associates Agreement.Conclusion: We describe the design and implementation of an RDW at a large academic healthcare system that uses a distinctive atomic design where data are stored at a high level of granularity. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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