Multichannel CNN Model for Biomedical Entity Reorganization.

Biomedical researchers and biologists often search a large amount of literature to find the relationship between biological entities, such as drug-drug and compound-protein. With the proliferation of medical literature and the development of deep learning, the automatic extraction of biological enti...

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Published in:BioMed Research International pp. 1 - 12
Main Authors: Singh, Ajay Kumar, Khan, Ihtiram Raza, Khan, Shakir, Pant, Kumud, Debnath, Sandip, Miah, Shahajan
Format: equations & formulas research tables/charts Journal Article
Published: Wiley-Blackwell 3/19/2022
Online Access:View this record in EBSCOhost
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      jtl: BioMed Research International
      issn: 23146133
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      dt: 3/19/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        155845622
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        155845622
        10.1155/2022/5765629
        155845622
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        atl: Multichannel CNN Model for Biomedical Entity Reorganization.
      aug:
        au:
          Singh, Ajay Kumar
          Khan, Ihtiram Raza
          Khan, Shakir
          Pant, Kumud
          Debnath, Sandip
          Miah, Shahajan
        affil: Mody University of Science and Technology, India
      sug:
        subj:
          Research, Medical
          Information Retrieval
          Neural Networks (Computer) Utilization
          Data Quality
          Human
          Deep Learning Methods
          Semantics
          Data Mining
      ab: Biomedical researchers and biologists often search a large amount of literature to find the relationship between biological entities, such as drug-drug and compound-protein. With the proliferation of medical literature and the development of deep learning, the automatic extraction of biological entity interaction relationships from literature has shown great potential. The fundamental scope of this research is that the approach described in this research uses technologies like dynamic word vectors and multichannel convolution to learn a larger variety of relational expression semantics, allowing it to detect more entity connections. The extraction of biological entity relationships is the foundation for achieving intelligent medical care, which may increase the effectiveness of intelligent medical question answering and enhance the development of precision healthcare. In the past, deep learning methods have achieved specific results, but there are the following problems: the model uses static word vectors, which cannot distinguish polysemy; the weight of words is not considered, and the extraction effect of long sentences is poor; the integration of various models can improve the sample imbalance problem, the model is more complex. The purpose of this work is to create a global approach for eliminating different physical entity links, such that the model can effectively extract the interpretation of the expression relationship without having to develop characteristics manually. To this end, a deep multichannel CNN model (MC-CNN) based on the residual structure is proposed, generating dynamic word vectors through BERT (Bidirectional Encoder Representation from Transformers) to improve the accuracy of lexical semantic representation and uses multihead attention to capture the dependencies of long sentences and by designing the Ranking loss function to replace the multimodel ensemble to reduce the impact of sample imbalance. Tested on multiple datasets, the results show that the proposed method has good performance.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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