Validation of the Modified Checklist for Autism in Toddlers, Revised with Follow-up in a Population Sample of 30-Month-Old Children in Iceland: A Prospective Approach.

The Modified Checklist for Autism in Toddlers, Revised with Follow-up was validated on a population sample in Reykjavik, Iceland. The participants (N = 1585) were screened in well-child care at age 30 months and followed up for at least 2 years to identify autism cases. The sensitivity, specificity,...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 52; no. 4; pp. 1507 - 1523
Autores principales: Jonsdottir, Sigridur Loa, Saemundsen, Evald, Jonsson, Brynjolfur Gauti, Rafnsson, Vilhjalmur
Formato: research tables/charts Journal Article
Publicado: Springer Nature Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10803-021-05053-1
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        atl: Validation of the Modified Checklist for Autism in Toddlers, Revised with Follow-up in a Population Sample of 30-Month-Old Children in Iceland: A Prospective Approach.
      aug:
        au:
          Jonsdottir, Sigridur Loa
          Saemundsen, Evald
          Jonsson, Brynjolfur Gauti
          Rafnsson, Vilhjalmur
        affil: State Diagnostic and Counseling Center, Digranesvegur 5, 200, Kopavogur, Iceland
      sug:
        subj:
          Autism Spectrum Disorder Diagnosis
          Instrument Validation
          Early Diagnosis
          Human
          Prospective Studies
          Checklists
          Iceland
          Health Screening
          Sensitivity and Specificity
          Predictive Value of Tests
          Severity of Illness
          Descriptive Statistics
      ab: The Modified Checklist for Autism in Toddlers, Revised with Follow-up was validated on a population sample in Reykjavik, Iceland. The participants (N = 1585) were screened in well-child care at age 30 months and followed up for at least 2 years to identify autism cases. The sensitivity, specificity, positive and negative predictive values were 0.62, 0.99, 0.72, and 0.99, respectively. True-positive children were diagnosed 10 months earlier than false-negative children. Autism symptom severity and the proportions of children with verbal and performance IQs/DQs < 70 were similar between groups. Although the sensitivity was suboptimal, the screening contributed to lowering the age at diagnosis for many children. Adding autism-specific screening to the well-child care program should be considered.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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