Exploring episodic and semantic contributions to past and future thinking performance in Korsakoff's syndrome.

Korsakoff's syndrome (KS) is a neuropsychiatric disorder characterized by severe declarative memory disruption. While episodic memory deficits and confabulation are well documented, it remains unclear to what extent semantic memory is compromised in this syndrome. Moreover, how such impairments rela...

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Publicado en:Memory & Cognition Vol. 50; no. 3; pp. 630 - 641
Autores principales: Janssen, Julie, Oudman, Erik, Irish, Muireann, Postma, Albert
Formato: Artículo
Publicado: Springer Nature Apr2022
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Springer Nature
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        10.3758/s13421-021-01262-2
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        atl: Exploring episodic and semantic contributions to past and future thinking performance in Korsakoff's syndrome.
      aug:
        au:
          Janssen, Julie
          Oudman, Erik
          Irish, Muireann
          Postma, Albert
        affil:
          Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
          Korsakoff Center Slingedael, Rotterdam, The Netherlands
          School of Psychology and Brain and Mind Centre, The University of Sydney, Sydney, Australia
      su:
        Task performance
        Episodic memory
        Thought & thinking
        Research
        Semantic memory
        Korsakoff's syndrome
        Statistical correlation
      sug:
        subj:
          Task performance
          Episodic memory
          Thought & thinking
          Research
          Semantic memory
          Korsakoff's syndrome
          Statistical correlation
      keyword:
        Confabulation
        Dementia
        Imagination
        Prospection
        Confabulation
        Dementia
        Imagination
        Prospection
      ab: Korsakoff's syndrome (KS) is a neuropsychiatric disorder characterized by severe declarative memory disruption. While episodic memory deficits and confabulation are well documented, it remains unclear to what extent semantic memory is compromised in this syndrome. Moreover, how such impairments relate to the capacity for future-oriented thinking remains unknown. Here, we sought to determine the extent to which episodic and semantic forms of past and future thinking are impacted in KS and the interrelationship between different classes of memory in this syndrome. Twenty patients with KS and 17 matched healthy controls took part in this study. We included well-established indices of past and future thinking capacity, enabling us to compare episodic (event-based) versus semantic (nonpersonal knowledge) across past and future conditions. We also included a novel event generation task to probe implausible event simulation (i.e., spending a day on the moon). Our findings revealed marked impairments in KS across all forms of past and future thinking, as well as the generation of episodic details on the implausible event simulation task. Correlation analyses revealed significant associations between implausible event construction and episodic and semantic future thinking in KS; however, no significant associations were found between future thinking performance and confabulation. This study is the first, to our knowledge, to reveal striking impairments in the capacity for past and future thinking across episodic and semantic domains in KS. Our findings resonate with current theoretical perspectives in which the lines between episodic and semantic memory systems are viewed as increasingly blurred.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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