Non-invasive imaging as the cornerstone of cardiovascular precision medicine.

Aims To provide an overview of the role of cardiovascular (CV) imaging in facilitating and advancing the field of precision medicine in CV disease. Methods and results Non-invasive CV imaging is essential to accurately and efficiently phenotype patients with heart disease, including coronary artery...

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Publicado en:European Heart Journal - Cardiovascular Imaging Vol. 23; no. 4; pp. 465 - 476
Autores principales: Achenbach, Stephan, Fuchs, Friedrich, Goncalves, Alexandra, Kaiser-Albers, Claudia, Ali, Ziad A, Bengel, Frank M, Dimmeler, Stefanie, Fayad, Zahi A, Mebazaa, Alexandre, Meder, Benjamin, Narula, Jagat, Shah, Amil, Sharma, Sanjay, Voigt, Jens-Uwe, Plein, Sven
Formato: diagnostic images tables/charts Journal Article
Publicado: Oxford University Press / USA Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Oxford University Press / USA
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        atl: Non-invasive imaging as the cornerstone of cardiovascular precision medicine.
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        au:
          Achenbach, Stephan
          Fuchs, Friedrich
          Goncalves, Alexandra
          Kaiser-Albers, Claudia
          Ali, Ziad A
          Bengel, Frank M
          Dimmeler, Stefanie
          Fayad, Zahi A
          Mebazaa, Alexandre
          Meder, Benjamin
          Narula, Jagat
          Shah, Amil
          Sharma, Sanjay
          Voigt, Jens-Uwe
          Plein, Sven
        affil: Department of Cardiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Universitätsklinikum Erlangen Medizinische Klinik 2—Kardiologie und Angiologie , Ulmenweg 18, 91054 Erlangen, Germany
      sug:
        subj:
          Cardiovascular Diseases
          Individualized Medicine
          Diagnostic Imaging
          Cardiovascular System Radiography
          Phenotype
          Coronary Arteriosclerosis
          Heart Diseases
          Heart Failure
          Echocardiography
          Tomography, X-Ray Computed
          Magnetic Resonance Imaging
          Coronary Angiography
      ab: Aims To provide an overview of the role of cardiovascular (CV) imaging in facilitating and advancing the field of precision medicine in CV disease. Methods and results Non-invasive CV imaging is essential to accurately and efficiently phenotype patients with heart disease, including coronary artery disease (CAD) and heart failure (HF). Various modalities, such as echocardiography, nuclear cardiology, cardiac computed tomography (CT), cardiovascular magnetic resonance (CMR), and invasive coronary angiography, and in some cases a combination, can be required to provide sufficient information for diagnosis and management. Taking CAD as an example, imaging is essential for the detection and functional assessment of coronary stenoses, as well as for the quantification of cardiac function and ischaemic myocardial damage. Furthermore, imaging may detect and quantify coronary atherosclerosis, potentially identify plaques at increased risk of rupture, and guide coronary interventions. In patients with HF, imaging helps identify specific aetiologies, quantify damage, and assess its impact on cardiac function. Imaging plays a central role in individualizing diagnosis and management and to determine the optimal treatment for each patient to increase the likelihood of response and improve patient outcomes. Conclusions Advances in all imaging techniques continue to improve accuracy, sensitivity, and standardization of functional and prognostic assessments, and identify established and novel therapeutic targets. Combining imaging with artificial intelligence, machine learning and computer algorithms, as well as with genomic, transcriptomic, proteomic, and metabolomic approaches, will become state of the art in the future to understand pathologies of CAD and HF, and in the development of new, targeted therapies.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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