Two-Stage Total Hip Arthroplasty for Primary Advanced Septic Arthritis of the Hip in Adults.

Background. Comparing the outcomes of debridement and total hip arthroplasty (THA) with antibiotic-loaded spacer implantation and subsequent THA for the treatment of patients affected by primary advanced septic arthritis (SA) of the hip in adults. Methods. All of the 20 patients (20 hips) underwent...

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Published in:BioMed Research International pp. 1 - 10
Main Authors: Li, Zhenzhong, Wei, Congcong, Li, Xiangke, Yao, Mengxuan, Li, Huijie
Format: diagnostic images research tables/charts Journal Article
Published: Wiley-Blackwell 4/4/2022
Online Access:View this record in EBSCOhost
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      dt: 4/4/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/8387465
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        atl: Two-Stage Total Hip Arthroplasty for Primary Advanced Septic Arthritis of the Hip in Adults.
      aug:
        au:
          Li, Zhenzhong
          Wei, Congcong
          Li, Xiangke
          Yao, Mengxuan
          Li, Huijie
        affil: Department of Orthopedics, Handan First Hospital, Handan, 056000 Hebei, China
      sug:
        subj:
          Arthroplasty, Replacement, Hip
          Arthritis, Infectious Therapy
          Hip Joint Surgery
          Treatment Outcomes
          Antibiotics Administration and Dosage
          Surgical Debridement
          Recurrence
          Scales
          Visual Analog Scaling
          Leg Length Inequality
          Time Factors
          After Care
          Functional Status
          Human
          Male
          Female
          Adult
          Middle Age
          Data Analysis Software
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background. Comparing the outcomes of debridement and total hip arthroplasty (THA) with antibiotic-loaded spacer implantation and subsequent THA for the treatment of patients affected by primary advanced septic arthritis (SA) of the hip in adults. Methods. All of the 20 patients (20 hips) underwent two-stage surgery. Nine patients were submitted to surgical debridement first and then THA (group 1), while 11 patients were treated with antibiotic-loaded spacer and subsequent THA (group 2). Patients were evaluated based on the recurrence of infection, Harris hip score, visual analogue scale (VAS) pain score, and leg length discrepancy. Results. No cases of infection, deep vein thrombosis, death, and loosening of the hip prosthesis were observed during follow-up. The mean follow-up time was 29.09 ± 10.80 months in group 1 and 28.22 ± 14.80 months in group 2. Before the THA surgery, the mean leg length discrepancy was 2.80 ± 2.03 cm in group 1 and 0.50 ± 0.23 cm in group 2 (P < 0.05). In the latest follow-up, the Harris hip scores of patients were 90.33 ± 4.85 in group 1 and 94.36 ± 2.34 in group 2 (P < 0.05), respectively. There was no statistically significant difference in the VAS pain score of the hip between the two groups (P > 0.05). Conclusions. Debridement and antibiotic-loaded spacer and subsequent THA were effective in eradicating the infection for advanced SA. However, antibiotic-loaded spacer and subsequent THA was superior for effectively maintaining the length of the lower limb and function of the hip.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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