PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study.
Background Blood lipids and glucose levels dysregulation represent potential mechanisms intermediating the adverse cardiovascular effects of ambient particulate matter (PM) exposure. This study aims to estimate the effect of long-term PM10 exposure on blood lipids and glucose levels and to assess th...
| Published in: | European Journal of Public Health Vol. 32; no. 2; pp. 281 - 289 |
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| Main Authors: | , , , , , , |
| Format: | pictorial research tables/charts Journal Article |
| Published: |
Oxford University Press / USA
Apr2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=156110171&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 156110171 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11011262 BHW jtl: European Journal of Public Health issn: 11011262 maglogo: N pubinfo: dt: Apr2022 vid: 32 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 156110171 156110171 156110171 10.1093/eurpub/ckab190 156110171 ppf: 281 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: PM10 exposure interacts with abdominal obesity to increase blood triglycerides: a cross-sectional linkage study. aug: au: Gaio, Vânia Roquette, Rita Monteiro, Alexandra Ferreira, Joana Lopes, Diogo Dias, Carlos Matias Nunes, Baltazar affil: Department of Epidemiology, Instituto Nacional de Saúde Doutor Ricardo Jorge IP (INSA, IP) , Lisboa, Portugal sug: subj: Environmental Exposure Adverse Effects Particulate Matter Adverse Effects Abdominal Fat Obesity Complications Triglycerides Blood Blood Glucose Analysis Human Cross Sectional Studies Mediation Analysis Particulate Matter Evaluation Environmental Monitoring Portugal Models, Statistical Lipids Blood Confidence Intervals Descriptive Statistics Cholesterol Blood Lipoproteins, LDL Cholesterol Blood Glycated Hemoglobin Blood Male Female Adult Middle Age Aged Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background Blood lipids and glucose levels dysregulation represent potential mechanisms intermediating the adverse cardiovascular effects of ambient particulate matter (PM) exposure. This study aims to estimate the effect of long-term PM10 exposure on blood lipids and glucose levels and to assess the potential mediation and/or modification action of abdominal obesity (AO) (waist-to-height ratio). Methods Our study was based on 2,390 participants of the first Portuguese Health Examination Survey (INSEF, 2015) with available data on blood lipids and glucose parameters and living within a 30-km radius of an air quality monitoring station with available PM10 measurements. PM10 concentrations were acquired from the air quality monitoring network of the Portuguese Environment Agency. Generalized linear models were used to assess the effect of 1-year PM10 exposure on blood lipids and glucose levels. An interaction term was introduced in the models to test the modification action of AO. Results We found an association between PM10 and non-fasting blood triglycerides (TG) after adjustment for age, sex, education, occupation, lifestyles-related variables and temperature but only in participants with AO. Per each 1 µg/m3 PM10 increment, there was a 1.84% (95% confidence interval: 0.02–3.69) increase in TG. For the remaining blood lipid and glucose parameters, no associations were found. Conclusions Our study demonstrates that even at low levels of exposure, long-term PM10 exposure interacts with AO to increase blood TG. Our findings suggest that reducing both AO prevalence and PM10 below current standards would result in additional health benefits for the population. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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