Alternation of nasopharyngeal microbiota in healthy youth is associated with environmental factors: implication for respiratory diseases.
The nasopharynx is a key niche of the upper respiratory tract which contains many commensal bacteria and potential pathogens. Dysbiosis of the nasopharyngeal (NP) microbiota is associated with a variety of respiratory diseases. Little is known about NP flora in healthy youth, nor about its relations...
| Publicado en: | International Journal of Environmental Health Research Vol. 32; no. 5; pp. 952 - 963 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
May2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=156120787&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 156120787 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: May2022 vid: 32 iid: 5 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 156120787 145550488 156120787 156120787 10.1080/09603123.2020.1810209 156120787 ppf: 952 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Alternation of nasopharyngeal microbiota in healthy youth is associated with environmental factors: implication for respiratory diseases. aug: au: Zhao, Hongcheng Chen, Shuaiyin Yang, Fan Wu, Huiying Ba, Yue Cui, Liuxin Chen, Ruiying Zhu, Jingyuan affil: Department of Environmental Health, College of Public Health, Zhengzhou University, Zhengzhou, China sug: subj: Nasopharynx Microbiology Microbiota Environment Adverse Effects Respiratory Tract Diseases Risk Factors Risk Assessment Human Genome Sequence Analysis RNA Seasons Gram-Negative Aerobic Bacteria Pathologic Processes Streptococcus Particulate Matter Temperature China Female Male Young Adult Female Male ab: The nasopharynx is a key niche of the upper respiratory tract which contains many commensal bacteria and potential pathogens. Dysbiosis of the nasopharyngeal (NP) microbiota is associated with a variety of respiratory diseases. Little is known about NP flora in healthy youth, nor about its relationship with environmental factors. We characterized NP microbiota using the 16S rRNA gene sequencing method, and compared microbial composition from subjects sampled in Spring and Fall when exposed to different environmental factors. Results showed that beta diversity was significantly different. Phyla Acidobacteria, Gemmatimonadetes, and genus Symbiobacterium were positively associated with PM2.5. Genera Streptococcus, Prevotella, and [Prevotella] were positively correlated with temperature (T). Ozone (O3) was associated with these floras for exposure that occurred 30 days prior to collection. These preliminary data suggest that the change in environmental factors between spring and fall can influence the composition of the NP microbiota, characterized by a significant correlation to specific taxa. These changes in NP microbiota might be a potential risk factor for respiratory disease. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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