Six-minute walk distance in healthy subjects: reference standards from a general population sample.
Introduction: The 6-min walking distance (6MWD) test is a useful tool to obtain a measure of functional exercise capacity. However, reference equations have been mainly based on selected populations or small samples. The purpose of this study was to determine the reference equations to predict the 6...
| Publicado en: | Respiratory Research Vol. 23; no. 1; pp. 1 - 10 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
BioMed Central
4/5/2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=156123736&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 156123736 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14659921 1D0T jtl: Respiratory Research issn: 14659921 maglogo: N pubinfo: dt: 4/5/2022 vid: 23 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 156123736 156123736 NLM35382813 10.1186/s12931-022-02003-y NLM35382813 156123736 ppf: 1 ppct: 9 formats: tig: atl: Six-minute walk distance in healthy subjects: reference standards from a general population sample. aug: au: Cazzoletti, Lucia Zanolin, Maria Elisabetta Dorelli, Gianluigi Ferrari, Pietro Dalle Carbonare, Luca Giuseppe Crisafulli, Ernesto Alemayohu, Mulubirhan Assefa Olivieri, Mario Verlato, Giuseppe Ferrari, Marcello affil: Unit of Epidemiology & Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Strada Le Grazie, 8, 37134, Verona, Italy sug: subj: Body Height Walking Child Exercise Test Female Research Subjects Aged Weights and Measures Adult Reference Values Male Infant Child, Preschool Middle Age Clinical Assessment Tools Questionnaires Exercise of Self-Care Agency Scale Child: 6-12 years Aged: 65+ years Adult: 19-44 years Infant: 1-23 months Child, Preschool: 2-5 years Middle Aged: 45-64 years Female Male ab: Introduction: The 6-min walking distance (6MWD) test is a useful tool to obtain a measure of functional exercise capacity. However, reference equations have been mainly based on selected populations or small samples. The purpose of this study was to determine the reference equations to predict the 6MWD in a large Italian population sample of healthy adults of a wide age range.Methods: In the frame of the multi case-control population-based study Gene Environment Interaction in Respiratory Diseases (GEIRD), we studied 530 healthy subjects: 287 females ranging 21-76 and 243 males ranging 21-78 years of age. We measured 6MWD, demographic and anthropometric data and collected the reported physical activity. A multiple linear regression model for the 6MWD included age, age2, height, weight and physical activity for both sex equations. The two-way interaction age-height and age-weight and the quadratic terms of weight and height were also tested for inclusion separately in each model.Results: The mean ± SD for 6MWD was 581.4 ± 66.5 m (range 383-800 m) for females and 608.7 ± 80.1 m (range 410-875 m) for males. The reference equations were 6MWD = 8.10*age + 1.61*heightcm-0.99*weightkg + 22.58*active-0.10*age2 + 222.55 for females (R squared = 0.238) and 6MWD = 26.80*age + 8.46*heightcm-0.45*weightkg-2.54*active-0.06*age2-0.13*age*heightcm-890.18 for males (R squared = 0.159), where "active" is 1 when the subject is physically active, 0 otherwise.Conclusion: This study is the first to describe the 6MWD in a large population sample of young, middle aged and elderly healthy Caucasian subjects, and to determine reference equations. These findings will help to improve the evaluation of Italian and European patients with diseases influencing their functional capacity. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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