Spatial attention impairments are characterized by specific electro-encephalographic correlates and partially mediate the association between early life stress and anxiety.

Although impaired attention is a diagnostic feature of anxiety disorders, we lack an understanding of which aspects of attention are impaired, the neurobiological basis of these impairments, and the contribution of stressors. To address these gaps in knowledge, we developed and tested behavioral tas...

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Publicado en:Cognitive, Affective & Behavioral Neuroscience Vol. 22; no. 2; pp. 414 - 429
Autores principales: Keller, Arielle S., Ling, Ruth, Williams, Leanne M.
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Springer Nature
      place: New York, New York
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        10.3758/s13415-021-00963-0
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        atl: Spatial attention impairments are characterized by specific electro-encephalographic correlates and partially mediate the association between early life stress and anxiety.
      aug:
        au:
          Keller, Arielle S.
          Ling, Ruth
          Williams, Leanne M.
        affil: Graduate Program in Neurosciences, Stanford University, Stanford, CA, USA
      sug:
        subj:
          Attention Evaluation
          Electroencephalography
          Task Performance and Analysis Evaluation
          Anxiety Complications
          Spatial Perception
          Stress, Psychological Complications
          Human
          Adolescence
          Adult
          Anxiety Symptoms
          Affect
          Life Change Events Evaluation
          Mental Health
          Severity of Illness
          Adolescent: 13-18 years
          Adult: 19-44 years
      ab: Although impaired attention is a diagnostic feature of anxiety disorders, we lack an understanding of which aspects of attention are impaired, the neurobiological basis of these impairments, and the contribution of stressors. To address these gaps in knowledge, we developed and tested behavioral tasks designed to parse the subdomains of attention impairments associated with anxiety symptoms and used electro-encephalographic (EEG) recordings to probe the neural basis of attentional performance. Participants were n = 55 individuals aged 18-35 with mild-to-moderate mood and anxiety symptoms. We also assessed stressful life events that may impact mental health and attention abilities, including stressors that occurred in early life before age 18 years. Severity of anxiety was found to be specifically associated with impairments in spatial attention but not feature-based attention. These impairments in spatial attention also partially mediated the association between early-life stressors and anxiety symptoms. Impairments in spatial selective attention were associated with decreased posterior alpha oscillations in EEG recordings in a subsample of participants, whereas spatial divided attention impairments were associated with decreased frontocentral theta oscillations. Our results provide a thorough characterization of attention impairments associated with anxiety, their EEG correlates, and the impact of stressors both in early life and adulthood.
      pubtype: Academic Journal
      doctype:
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        research
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      ougenre: Article
    language: English
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