How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?

Underrepresentation of individuals with limited English proficiency (LEP) who speak Spanish is ongoing in phase 3 biomedical clinical trials and exacerbates health inequity. This article suggests strategies for increasing representation of Spanish speakers in clinical rials by emphasizing the import...

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Publicado en:AMA Journal of Ethics Vol. 24; no. 4; pp. 319 - 326
Autores principales: Alhalel, Jonathan, Francone, Nicolás, Post, Sharon, O'Brian, Catherine A., Simon, Melissa A.
Formato: questionnaire/scale Journal Article
Publicado: American Medical Association Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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        10.1001/amajethics.2022.319
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        atl: How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?
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          Alhalel, Jonathan
          Francone, Nicolás
          Post, Sharon
          O'Brian, Catherine A.
          Simon, Melissa A.
        affil: fourth-year medical student at the Northwestern University Feinberg School of Medicine in Chicago, Illinois
      sug:
        subj:
          Research Methodology
          English Language
          Communication Skills
          Ethnic Groups
          Research Subject Recruitment
          Healthcare Disparities
          Hispanic Americans
          Quality of Life
      ab: Underrepresentation of individuals with limited English proficiency (LEP) who speak Spanish is ongoing in phase 3 biomedical clinical trials and exacerbates health inequity. This article suggests strategies for increasing representation of Spanish speakers in clinical rials by emphasizing the importance of early engagement with Spanish language communities, inclusive participant recruitment, and collaborative trial design and implementation. Although investigators and institutions administering government-funded research must meet federal requirements for language assistance, journal editors, peer reviewers, institutional review board members, academic health centers, and all beneficiaries of the biomedical and behavioral research enterprise in the United States must motivate linguistic inclusion.
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