Deep learning-based classification of posttraumatic stress disorder and depression following trauma utilizing visual and auditory markers of arousal and mood.

Background: Visual and auditory signs of patient functioning have long been used for clinical diagnosis, treatment selection, and prognosis. Direct measurement and quantification of these signals can aim to improve the consistency, sensitivity, and scalability of clinical assessment. Currently, we i...

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Publicado en:Psychological Medicine Vol. 52; no. 5; pp. 957 - 968
Autores principales: Schultebraucks, Katharina, Yadav, Vijay, Shalev, Arieh Y., Bonanno, George A., Galatzer-Levy, Isaac R.
Formato: research tables/charts Journal Article
Publicado: Cambridge University Press Apr2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2022
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      pub: Cambridge University Press
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        10.1017/S0033291720002718
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        atl: Deep learning-based classification of posttraumatic stress disorder and depression following trauma utilizing visual and auditory markers of arousal and mood.
      aug:
        au:
          Schultebraucks, Katharina
          Yadav, Vijay
          Shalev, Arieh Y.
          Bonanno, George A.
          Galatzer-Levy, Isaac R.
        affil: Department of Emergency Medicine, Vagelos School of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, USA
      sug:
        subj:
          Deep Learning
          Stress Disorders, Post-Traumatic
          Depression
          Trauma
          Machine Learning
          Semantics
          Human
          Semantic Analysis
          Emergency Service
          Patient Admission
          Interviews
          Emotions
          Speech
      ab: Background: Visual and auditory signs of patient functioning have long been used for clinical diagnosis, treatment selection, and prognosis. Direct measurement and quantification of these signals can aim to improve the consistency, sensitivity, and scalability of clinical assessment. Currently, we investigate if machine learning-based computer vision (CV), semantic, and acoustic analysis can capture clinical features from free speech responses to a brief interview 1 month post-trauma that accurately classify major depressive disorder (MDD) and posttraumatic stress disorder (PTSD). Methods: N = 81 patients admitted to an emergency department (ED) of a Level-1 Trauma Unit following a life-threatening traumatic event participated in an open-ended qualitative interview with a para-professional about their experience 1 month following admission. A deep neural network was utilized to extract facial features of emotion and their intensity, movement parameters, speech prosody, and natural language content. These features were utilized as inputs to classify PTSD and MDD cross-sectionally. Results: Both video- and audio-based markers contributed to good discriminatory classification accuracy. The algorithm discriminates PTSD status at 1 month after ED admission with an AUC of 0.90 (weighted average precision = 0.83, recall = 0.84, and f1-score = 0.83) as well as depression status at 1 month after ED admission with an AUC of 0.86 (weighted average precision = 0.83, recall = 0.82, and f1-score = 0.82). Conclusions: Direct clinical observation during post-trauma free speech using deep learning identifies digital markers that can be utilized to classify MDD and PTSD status.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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