Intrapulmonary Pharmacokinetic Modeling and Simulation of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Patients With Pneumonia and Healthy Subjects.

Cefiderocol is a siderophore cephalosporin for the treatment of infections caused by gram‐negative bacteria including carbapenem‐resistant strains. The aim of this study was to develop an intrapulmonary pharmacokinetic (PK) model of cefiderocol and assess the PK profile in lungs. An intrapulmonary P...

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Publicado en:Journal of Clinical Pharmacology Vol. 62; no. 5; pp. 670 - 681
Autores principales: Kawaguchi, Nao, Katsube, Takayuki, Echols, Roger, Wajima, Toshihiro, Nicolau, David P.
Formato: equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell May2022
Acceso en línea:Ver este registro en EBSCOhost