Synthesis, molecular docking and ADMET prediction of novel swertiamarin analogues for the restoration of type-2 diabetes: an enzyme inhibition assay.

Swertiamarin is a lead, biologically active compound obtained from Enicostemma littorale Blume and known to be identified for the anti-diabetic activity. Present work comprises the synthesis and structural optimization of seven novel swertiamarin analogues and those were not being reported elsewhere...

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Publicado en:Natural Product Research Vol. 36; no. 9; pp. 2197 - 2208
Autores principales: Kumar, Satyender, Niguram, Prakash, Bhat, Vedika, Jinagal, Seema, Jairaj, Vinod, Chauhan, Neelam
Formato: Journal Article
Publicado: Taylor & Francis Ltd May2022
Acceso en línea:Ver este registro en EBSCOhost