Global DNA methylation and cellular 5-methylcytosine and H4 acetylated patterns in primary and secondary dormant seeds of Capsella bursa-pastoris (L.) Medik. (shepherd's purse).

Despite the importance of dormancy and dormancy cycling for plants' fitness and life cycle phenology, a comprehensive characterization of the global and cellular epigenetic patterns across space and time in different seed dormancy states is lacking. Using Capsella bursa-pastoris (L.) Medik. (shepher...

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Publicado en:Protoplasma Vol. 259; no. 3; pp. 595 - 615
Autores principales: Gomez-Cabellos, Sara, Toorop, Peter E., Cañal, María Jesús, Iannetta, Pietro P. M., Fernández-Pascual, Eduardo, Pritchard, Hugh W., Visscher, Anne M.
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature May2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00709-021-01678-2
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        atl: Global DNA methylation and cellular 5-methylcytosine and H4 acetylated patterns in primary and secondary dormant seeds of Capsella bursa-pastoris (L.) Medik. (shepherd's purse).
      aug:
        au:
          Gomez-Cabellos, Sara
          Toorop, Peter E.
          Cañal, María Jesús
          Iannetta, Pietro P. M.
          Fernández-Pascual, Eduardo
          Pritchard, Hugh W.
          Visscher, Anne M.
        affil: Department of Comparative Plant and Fungal Biology, Royal Botanic Gardens, Kew, Wakehurst Place, RH17 6TN, Ardingly, West Sussex, UK
      sug:
        subj:
          DNA Methylation
          Heterocyclic Compounds Analysis
          Seeds Metabolism
          Plant Physiology
          Histones Metabolism
          Seeds Analysis
          Epigenomics
          Enzyme-Linked Immunosorbent Assay
          Plant Shoots Analysis
          Plant Shoots Metabolism
          Signal Transduction
          Genome
      ab: Despite the importance of dormancy and dormancy cycling for plants' fitness and life cycle phenology, a comprehensive characterization of the global and cellular epigenetic patterns across space and time in different seed dormancy states is lacking. Using Capsella bursa-pastoris (L.) Medik. (shepherd's purse) seeds with primary and secondary dormancy, we investigated the dynamics of global genomic DNA methylation and explored the spatio-temporal distribution of 5-methylcytosine (5-mC) and histone H4 acetylated (H4Ac) epigenetic marks. Seeds were imbibed at 30 °C in a light regime to maintain primary dormancy, or in darkness to induce secondary dormancy. An ELISA-based method was used to quantify DNA methylation, in relation to total genomic cytosines. Immunolocalization of 5-mC and H4Ac within whole seeds (i.e., including testa) was assessed with reference to embryo anatomy. Global DNA methylation levels were highest in prolonged (14 days) imbibed primary dormant seeds, with more 5-mC marked nuclei present only in specific parts of the seed (e.g., SAM and cotyledons). In secondary dormant seeds, global methylation levels and 5-mC signal where higher at 3 and 7 days than 1 or 14 days. With respect to acetylation, seeds had fewer H4Ac marked nuclei (e.g., SAM) in deeper dormant states, for both types of dormancy. However, the RAM still showed signal after 14 days of imbibition under dormancy-inducing conditions, suggesting a central role for the radicle/RAM in the response to perceived ambient changes and the adjustment of the seed dormancy state. Thus, we show that seed dormancy involves extensive cellular remodeling of DNA methylation and H4 acetylation.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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