Placental Tissues as Biomaterials in Regenerative Medicine.

Placental tissues encompass all the tissues which support fetal development, including the placenta, placental membrane, umbilical cord, and amniotic fluid. Since the 1990s there has been renewed interest in the use of these tissues as a raw material for regenerative medicine applications. Placental...

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Publicado en:BioMed Research International pp. 1 - 27
Autores principales: Roy, Annelise, Mantay, Morgan, Brannan, Courtney, Griffiths, Sarah
Formato: pictorial review tables/charts Journal Article
Publicado: Wiley-Blackwell 4/21/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 4/21/2022
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/6751456
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        atl: Placental Tissues as Biomaterials in Regenerative Medicine.
      aug:
        au:
          Roy, Annelise
          Mantay, Morgan
          Brannan, Courtney
          Griffiths, Sarah
        affil: Research and Development, StimLabs LLC, 1225 Northmeadow Parkway, Suite 104, Roswell, GA 30076, USA
      sug:
        subj:
          Placenta Physiology
          Biocompatible Materials
          Regeneration
          Fetal Development
          Fetal Membranes
          Umbilical Cord
          Amniotic Fluid
          Extracellular Space
          Collagen
          Glycosaminoglycans
          Glycoproteins
          Cytokines Metabolism
          Wound Healing
          Neovascularization, Physiologic
          Inflammation Prevention and Control
      ab: Placental tissues encompass all the tissues which support fetal development, including the placenta, placental membrane, umbilical cord, and amniotic fluid. Since the 1990s there has been renewed interest in the use of these tissues as a raw material for regenerative medicine applications. Placental tissues have been extensively studied for their potential contribution to tissue repair applications. Studies have attributed their efficacy in augmenting the healing process to the extracellular matrix scaffolds rich in collagens, glycosaminoglycans, and proteoglycans, as well as the presence of cytokines within the tissues that have been shown to stimulate re-epithelialization, promote angiogenesis, and aid in the reduction of inflammation and scarring. The compositions and properties of all birth tissues give them the potential to be valuable biomaterials for the development of new regenerative therapies. Herein, the development and compositions of each of these tissues are reviewed, with focus on the structural and signaling components that are relevant to medical applications. This review also explores current configurations and recent innovations in the use of placental tissues as biomaterials in regenerative medicine.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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