PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development.

Background: Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal circulation to mobilize skeletal calcium used for milk production. PTHrP...

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Bibliographic Details
Published in:Breast Cancer Research Vol. 24; no. 1; pp. 1 - 24
Main Authors: Grinman, Diego Y., Boras-Granic, Kata, Takyar, Farzin M., Dann, Pamela, Hens, Julie R., Marmol, Christina, Lee, Jongwon, Choi, Jungmin, Chodosh, Lewis A., Sola, Martin E. Garcia, Wysolmerski, John J.
Format: research Journal Article
Published: BioMed Central 4/19/2022
Online Access:View this record in EBSCOhost