Imaging Advancements in Nuclear Medicine: Pancreatic Neuroendocrine Tumor Localization and Treatment.
Background This case report details a 57-year-old African American man with pancreatic neuroendocrine tumors (NETs). The patient underwent positron emission tomography (PET) imaging using gallium Ga 68 dotatate, which localized the tumors. Selected tumors were treated with 4 doses of 200 mCi of lute...
| Published in: | Radiologic Technology Vol. 93; no. 5; pp. 431 - 437 |
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| Main Authors: | , , , , , , , , |
| Format: | case study diagnostic images tables/charts Journal Article |
| Published: |
American Society of Radiologic Technologists
May/Jun2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=156500254&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 156500254 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00338397 39J jtl: Radiologic Technology issn: 00338397 maglogo: N pubinfo: dt: May/Jun2022 vid: 93 iid: 5 pid: 7052 pub: American Society of Radiologic Technologists place: Alburquerque, New Mexico artinfo: ui: 156500254 156500254 156500254 156500254 ppf: 431 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Imaging Advancements in Nuclear Medicine: Pancreatic Neuroendocrine Tumor Localization and Treatment. aug: au: Palmer Stephens, Chelsea Street Beam, Asher Gray, Zack Mansfield, Julia Reves, Lexie Gray, Jennie Stamey, Alexa Collum, Matthew Vijayakumar, Vani affil: Director of the Master of Science in Nuclear Medicine Technology program and assistant professor for the Department of Clinical and Diagnostic Sciences at the University of Mississippi Medical Center, School of Health Related Professions in Jackson sug: subj: Pancreatic Neoplasms Radiography Neuroendocrine Tumors Radiography Pancreatic Neoplasms Radiotherapy Neuroendocrine Tumors Radiotherapy Nuclear Medicine Organometallic Compounds Therapeutic Use Treatment Outcomes Male Middle Age Positron-Emission Tomography Methods Gallium Diagnostic Use Radiopharmaceuticals Therapeutic Use Pancreatectomy Splenectomy Mesenteric Veins Surgery Neuroendocrine Tumors Symptoms Pancreatic Neoplasms Symptoms Middle Aged: 45-64 years Male ab: Background This case report details a 57-year-old African American man with pancreatic neuroendocrine tumors (NETs). The patient underwent positron emission tomography (PET) imaging using gallium Ga 68 dotatate, which localized the tumors. Selected tumors were treated with 4 doses of 200 mCi of lutetium Lu 177 dotatate during a period of 8 months. At the conclusion of treatment, the patient demonstrated improvement, progressing from bedbound and confused to ambulatory and coherent. In addition, the patient stated he felt no adverse effects. Discussion Pancreatic NETs are rare tumors affecting 0.001% of the population. These tumors are associated with various symptoms and are classified as functional or nonfunctional. Imaging modalities, such as computed tomography (CT), magnetic resonance (MR) imaging, and gallium Ga 68--labeled PET, are essential in detecting and evaluating pancreatic NETs. For patients with localized NETs, the primary treatment is surgery; however, the radiopharmaceuticals yttrium Y 90 microspheres and lutetium Lu 177 dotatate are used as therapy to treat nonresectable tumors. Conclusion Lutetium Lu 177 dotatate is used in NET cases that are deemed inoperable and for patients who are not responding to treatment. This case study demonstrates the effectiveness of combining imaging with Ga 68--labeled PET and treatment with lutetium Lu 177 dotatate. This treatment is not a cure but has been shown to improve a patient's quality of life. pubtype: Academic Journal doctype: case study diagnostic images tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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