Effect of the local probiotics in the therapy of periodontitis A randomized prospective study.

Objectives: The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in...

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Publicado en:International Journal of Dental Hygiene Vol. 20; no. 2; pp. 401 - 408
Autores principales: Minić, Ivan, Pejčić, Ana, Bradić‐Vasić, Marija
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Wiley-Blackwell May2022
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Dental Hygiene
      issn: 16015029
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      dt: May2022
      vid: 20
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        156508650
        156508650
        10.1111/idh.12509
        156508650
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        atl: Effect of the local probiotics in the therapy of periodontitis A randomized prospective study.
      aug:
        au:
          Minić, Ivan
          Pejčić, Ana
          Bradić‐Vasić, Marija
        affil: Department of Periodontology and Oral medicine, Medical faculty, University of Nis, Nis, Serbia
      sug:
        subj:
          Probiotics Therapeutic Use
          Periodontitis Therapy
          Dental Scaling
          Root Planing
          Treatment Outcomes Evaluation
          Combined Modality Therapy
          Human
          Randomized Controlled Trials
          Random Assignment
          Comparative Studies
          Prospective Studies
          Pretest-Posttest Design
          Periodontal Pocket
          Dental Plaque
          Descriptive Statistics
          Adult
          Middle Age
          Data Analysis Software
          Mann-Whitney U Test
          Adult: 19-44 years
          Middle Aged: 45-64 years
      ab: Objectives: The use of local probiotics in the therapy of periodontitis is reflected in their ability to antagonize periodontopathogens and modulates the immune response of the host to the presence of pathogenic microorganisms. The aim of this study was to investigate the use of local probiotics in the treatment of periodontitis as an adjunctive therapy to scaling and root planning (SRP). Methods: The study involved 80 patients diagnosed with periodontitis. All participants underwent SRP therapy. Semi‐solid probiotic was then locally applied to the periodontal pocket in randomly selected patients for the test group (40 of them). The other 40 patients were in the control group. Clinical parameters including periodontal pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI) were measured at baseline, and at 7 and 30 days after treatment. Results: Seven days after the applied therapy in the test and control group, there was a significant decrease in the values or BOP (p <.001), while the values of other parameters did not show a statistically significant difference (p <.05). One month after the therapy in both groups, there was a statistically significant difference in the values of all clinical parameters (p <.001). Conclusions: Based on the results of this pilot study, it can be said that, during periodontal treatment, topical application of probiotics in combination with SRP increases the effectiveness of conventional non‐surgical therapy of periodontitis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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