Assessment of cognitive function in long-term Hodgkin lymphoma survivors, results based on data from a major treatment center in Hungary.
Introduction: Nowadays, more than 80% of newly diagnosed classical Hodgkin lymphoma (HL) patients can be cured and become long-term survivors due to risk and response-adapted treatment strategies. A well-known side effect is cognitive dysfunction that appears in HL patients after chemotherapy. In th...
| Publicado en: | Supportive Care in Cancer Vol. 30; no. 6; pp. 5249 - 5259 |
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| Autores principales: | , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jun2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=156548672&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 156548672 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09414355 O1J jtl: Supportive Care in Cancer issn: 09414355 maglogo: N pubinfo: dt: Jun2022 vid: 30 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 156548672 155676126 156548672 NLM35274189 10.1007/s00520-022-06918-6 NLM35274189 156548672 ppf: 5249 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Assessment of cognitive function in long-term Hodgkin lymphoma survivors, results based on data from a major treatment center in Hungary. aug: au: Magyari, Ferenc Virga, István Simon, Zsófia Miltényi, Zsófia Illés, Anna Kósa, Karolina Ivánka, Tibor Berecz, Roland Égerházi, Anikó Illés, Árpád affil: Division of Haematology, Department of Internal Medicine, University of Debrecen, Debrecen, Hungary sug: subj: Hodgkin's Disease Drug Therapy Hodgkin's Disease Psychosocial Factors Survivors Psychosocial Factors Cognition Female Male Hungary Memory, Short Term Neuropsychological Tests Quality of Life Scales Ferrans and Powers Quality of Life Index Female Male ab: Introduction: Nowadays, more than 80% of newly diagnosed classical Hodgkin lymphoma (HL) patients can be cured and become long-term survivors due to risk and response-adapted treatment strategies. A well-known side effect is cognitive dysfunction that appears in HL patients after chemotherapy. In the present study, we aimed to measure cognitive dysfunction in our HL patients in this study and to find potential correlations between patient-related factors, the signs and symptoms of their diseases, or therapeutic factors.Methods: We carried out a computer-assisted assessment (CANTAB) of cognitive dysfunction in 118 patients. We examined the domains of visual memory, attention, working memory, and planning.Results: The median age of 64 females and 54 males at diagnosis was 29 (13-74) and 41 (21-81) years at the completion of CANTAB. Fifty-two percent of all patients showed cognitive impairment. Attention was impaired in 35% of patients, the working memory and planning were impaired in 25%, while visual memory was affected in 22%. All the three functions showed a significant association with inactive employments status. A close correlation was found between visual memory/working memory and planning, higher age at HL diagnosis or the completion of CANTAB test, and disability pensioner status.Discussion: Our investigation suggests that patients with inactive employment status and older age require enhanced attention. Their cognitive function and quality of life can be improved if they return to work or, if it is not possible, they receive a cognitive training. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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