Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies.
Introduction: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines. We aimed to develop and validate an objectively derived content search strategy containing generic search terms that can...
| Publicado en: | Journal of the Medical Library Association Vol. 110; no. 2; pp. 185 - 205 |
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| Autores principales: | , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
University of Pittsburgh, University Library System
Apr2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=156607462&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 156607462 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15365050 PI8 jtl: Journal of the Medical Library Association issn: 15365050 maglogo: N pubinfo: dt: Apr2022 vid: 110 iid: 2 pid: 60406 pub: University of Pittsburgh, University Library System place: Pittsburgh, Pennsylvania artinfo: ui: 156607462 156607462 156607462 10.5195/jmla.2022.1306 156607462 ppf: 185 ppct: 20 formats: fmt: @attributes: type: P tig: atl: Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies. aug: au: El Masri, Hiba McGuire, Treasure M. Dalais, Christine van Driel, Mieke Benham, Helen Hollingworth, Samantha A. affil: PhD Candidate, School of Pharmacy, The University of Queensland, Woolloongabba, QLD, Australia sug: subj: Literature Searching Methods Adverse Drug Event Risk Factors Drug Efficacy Evaluation Risk Assessment Methods Information Retrieval Methods Drugs, Prescription Therapeutic Use Drugs, Prescription Adverse Effects Subject Headings Human Sensitivity and Specificity Evaluation Multiple Sclerosis Drug Therapy Arthritis, Rheumatoid Drug Therapy Descriptive Statistics Precision Evaluation Comparative Studies Patient Preference Bibliography and References Information Storage Methods Nomenclature Information Retrieval Standards Lung Neoplasms Information Storage Standards Diabetes Mellitus, Type 2 Antirheumatic Agents Therapeutic Use ab: Introduction: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines. We aimed to develop and validate an objectively derived content search strategy containing generic search terms that can be adapted for any search for evidence on patient-based BRA of medicines for any therapeutic area. Methods: We used a robust multistep process to develop and validate the content search strategy: (1) we developed a bank of search terms derived from screening studies on patient-based BRA of medicines in various therapeutic areas, (2) we refined the proposed content search strategy through an iterative process of testing sensitivity and precision of search terms, and (3) we validated the final search strategy in PubMed by firstly using multiple sclerosis as a case condition and secondly computing its relative performance versus a published systematic review on patient-based BRA of medicines in rheumatoid arthritis. Results: We conceptualized a final search strategy to retrieve studies on patient-based BRA containing generic search terms grouped into two domains, namely the patient and the BRA of medicines (sensitivity 84%, specificity 99.4%, precision 20.7%). The relative performance of the content search strategy was 85.7% compared with a search from a published systematic review of patient preferences in the treatment of rheumatoid arthritis. We also developed a more extended filter, with a relative performance of 93.3% when compared with a search from a published systematic review of patient preferences in lung cancer. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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