Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases.

Background: The interferon response can influence the primary and metastatic activity of breast cancers and can interact with checkpoint immunotherapy to modulate its effects. Using N-ethyl-N-nitrosourea mutagenesis, we found a mouse with an activating mutation in oligoadenylate synthetase 2 (Oas2),...

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Publicado en:	Breast Cancer Research Vol. 24; no. 1; pp. 1 - 15
Autores principales:	Ho, Wing-Hong Jonathan, Law, Andrew M. K., Masle-Farquhar, Etienne, Castillo, Lesley E., Mawson, Amanda, O'Bryan, Moira K., Goodnow, Christopher C., Gallego-Ortega, David, Oakes, Samantha R., Ormandy, Christopher J.
Formato:	research Journal Article
Publicado:	BioMed Central 5/3/2022
Acceso en línea:	Ver este registro en EBSCOhost