Connections between Various Disorders: Combination Pattern Mining Using Apriori Algorithm Based on Diagnosis Information from Electronic Medical Records.

Objective. Short-term or long-term connections between different diseases have not been fully acknowledged. This study was aimed at exploring the network association pattern between disorders that occurred in the same individual by using the association rule mining technique. Methods. Raw data were...

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Published in:BioMed Research International pp. 1 - 17
Main Authors: Ma, He, Ding, Jingjing, Liu, Mei, Liu, Ying
Format: equations & formulas research tables/charts Journal Article
Published: Wiley-Blackwell 5/13/2022
Online Access:View this record in EBSCOhost
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      dt: 5/13/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        156864722
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        10.1155/2022/2199317
        156864722
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        atl: Connections between Various Disorders: Combination Pattern Mining Using Apriori Algorithm Based on Diagnosis Information from Electronic Medical Records.
      aug:
        au:
          Ma, He
          Ding, Jingjing
          Liu, Mei
          Liu, Ying
        affil: Department of Medical Records & Statistics, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221000, China
      sug:
        subj:
          Electronic Health Records
          Algorithms
          Data Mining
          Medical Records
          Diagnosis
          Human
          Descriptive Statistics
          Data Analysis Software
          International Classification of Diseases
          Male
          Female
          Middle Age
          Aged
          Aged, 80 and Over
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Objective. Short-term or long-term connections between different diseases have not been fully acknowledged. This study was aimed at exploring the network association pattern between disorders that occurred in the same individual by using the association rule mining technique. Methods. Raw data were extracted from the large-scale electronic medical record database of the affiliated hospital of Xuzhou Medical University. 1551732 pieces of diagnosis information from 144207 patients were collected from 2015 to 2020. Clinic diagnoses were categorized according to "International Classification of Diseases, 10th revision". The Apriori algorithm was used to explore the association patterns among those diagnoses. Results. 12889 rules were generated after running the algorithm at first. After threshold filtering and manual examination, 110 disease combinations (support ≥ 0.001 , confidence ≥ 60 % , lift > 1) with strong association strength were obtained eventually. Association rules about the circulatory system and metabolic diseases accounted for a significant part of the results. Conclusion. This research elucidated the network associations between disorders from different body systems in the same individual and demonstrated the usefulness of the Apriori algorithm in comorbidity or multimorbidity studies. The mined combinations will be helpful in improving prevention strategies, early identification of high-risk populations, and reducing mortality.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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