The potential role of diffusion weighted imaging in the diagnosis of early carotid and vertebral artery dissection.

Purpose: To investigate the role of the diffusion weighted imaging (DWI) in the acute dissection of internal carotid artery (ICA) and vertebral artery (VA) and assessing the length of intramural hematoma (IMH), caused by dissection. Methods: We analyzed 28 patients presenting with a dissection of th...

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Published in:Neuroradiology Vol. 64; no. 6; pp. 1135 - 1145
Main Authors: Almohammad, Mohammad, Dadak, Mete, Götz, Friedrich, Donnerstag, Frank, Tryc, Anita Blanka, Mahmoudi, Nima, Wattjes, Mike P.
Format: diagnostic images research tables/charts Journal Article
Published: Springer Nature Jun2022
Online Access:View this record in EBSCOhost
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      dt: Jun2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00234-021-02842-4
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        atl: The potential role of diffusion weighted imaging in the diagnosis of early carotid and vertebral artery dissection.
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          Almohammad, Mohammad
          Dadak, Mete
          Götz, Friedrich
          Donnerstag, Frank
          Tryc, Anita Blanka
          Mahmoudi, Nima
          Wattjes, Mike P.
        affil: Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Carotid Artery Dissections Diagnosis
          Vertebral Artery Dissections Diagnosis
          Hematoma Pathology
          Atherosclerosis Physiopathology
          Human
          Male
          Female
          Retrospective Design
          Tomography, X-Ray Computed
          Funding Source
          Image Processing, Computer Assisted
          Ischemic Stroke
          Male
          Female
      ab: Purpose: To investigate the role of the diffusion weighted imaging (DWI) in the acute dissection of internal carotid artery (ICA) and vertebral artery (VA) and assessing the length of intramural hematoma (IMH), caused by dissection. Methods: We analyzed 28 patients presenting with a dissection of the ICA and/or VA with respect to the presence of high signal intensity areas on DWI suggestive of dissection and 20 control subjects without arterial dissection, some with and some without atherosclerotic lesions. ICA or VA dissection was defined by clinical and imaging, computed tomography angiography (CTA), MR angiography (MRA), and digital subtraction angiography (DSA) findings. The length of DWI hyperintensity was compared to length of the occlusion or stenosis on the angiographic examination. Results: In 28 patients, 30 dissected arteries were analyzed. Time intervals from the onset of the first clinical symptoms to the radiological evaluation ranged from 1.5 h to 42 days. In 28 (93%) of the dissections, a high signal intensity of the affected artery was present on DWI. The measurement of the dissection length on DWI compared to DSA showed a mean deviation of 2.7 mm and a standard deviation of 3.7 mm. Conclusion: DWI is a highly sensitive and valuable pulse sequence for the detection of dissected cervical arteries even in the first hours after symptom onset. In contrast to CTA and MRA, DWI can be a potential tool for a reliable measurement of the dissection length.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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