A Dual Level Analysis with Evolutionary Computing and Swarm Models for Classification of Leukemia.

One of the major reasons of mortality in human beings is cancer, and there is an absolute necessity for doctors to identify and treat a person suffering from it. Leukemia is a group of blood cancers that usually originates in the bone marrow and results in very high number of abnormal cells. For the...

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Publicado en:BioMed Research International pp. 1 - 17
Autores principales: Prabhakar, Sunil Kumar, Ryu, Semin, Jeong, In cheol, Won, Dong-Ok
Formato: algorithm equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 5/26/2022
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
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    pubinfo:
      dt: 5/26/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/2052061
        157102724
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        atl: A Dual Level Analysis with Evolutionary Computing and Swarm Models for Classification of Leukemia.
      aug:
        au:
          Prabhakar, Sunil Kumar
          Ryu, Semin
          Jeong, In cheol
          Won, Dong-Ok
        affil: Department of Artificial Intelligence Convergence, Hallym University, Chuncheon, 24252 Gangwon, Republic of Korea
      sug:
        subj:
          Leukemia Diagnosis
          Leukemia Classification
          Human
          Microarray Analysis
          Multivariate Analysis
          Correlational Studies
          Computing Methodologies
          Comorbidity
      ab: One of the major reasons of mortality in human beings is cancer, and there is an absolute necessity for doctors to identify and treat a person suffering from it. Leukemia is a group of blood cancers that usually originates in the bone marrow and results in very high number of abnormal cells. For the diagnosis of cancer, microarray data serves as an important clinical application and serves as a great aid to the entire medical community. The dimensionality of the microarray data is too high, and so selection of suitable genes is quite an important step for the improvement of data classification. Therefore, for the prediction and diagnosis of cancer, there is an utmost necessity to select the most informative genes. In this work, Minimum Redundancy Maximum Relevance (MRMR), Signal to Noise Ratio (SNR), Multivariate Error Weight Uncorrelated Shrunken Centroid (EWUSC), and multivariate correlation-based feature selection (CFS) are chosen as initial feature selection techniques. Then, to select the most informative genes, five different kinds of evolutionary optimization techniques too are incorporated here such as African Buffalo Optimization (ABO), Artificial Bee Colony Optimization (ABCO), Cockroach Swarm Optimization (CSO), Imperialist Competitive Optimization (ICO), and Social Spider Optimization (SSO). Finally, the optimized values are fed through classification process and the best results are obtained when multivariate CFS with SSO is utilized and classified with Probabilistic Neural Network (PNN), and a high classification accuracy of 95.70% is obtained.
      pubtype: Academic Journal
      doctype:
        algorithm
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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