Molecular SARS-CoV-2 surveillance in Bavaria shows no Omicron transmission before the end of November 2021.

Background: Five SARS-CoV-2 variants are currently considered as variants of concern (VOC). Omicron was declared a VOC at the end of November 2021. Based on different diagnostic methods, the occurrence of Omicron was reported by 52 countries worldwide on December 7 2021. First notified by South Afri...

Descripción completa

Detalles Bibliográficos
Publicado en:Infection Vol. 50; no. 3; pp. 761 - 767
Autores principales: Flechsler, Jennifer, Eberle, Ute, Dangel, Alexandra, Hepner, Sabrina, Wimmer, Clara, Lutmayr, Johannes, Konrad, Regina, Berger, Carola, Weise, Laura, Sprenger, Annika, Zeitler, Jörg, Paravinja, Natali, Angermeier, Hildegard, Githure, George, Schmidt, Sandra, Treis, Bianca, Okeyo, Mercy, Liebl, Bernhard, Ackermann, Nikolaus, Sing, Andreas
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jun2022
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157151759&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 157151759
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        03008126
        NXO
      jtl: Infection
      issn: 03008126
      maglogo: N
    pubinfo:
      dt: Jun2022
      vid: 50
      iid: 3
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        157151759
        155486964
        157151759
        157151759
        10.1007/s15010-022-01767-1
        157151759
      ppf: 761
      ppct: 6
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Molecular SARS-CoV-2 surveillance in Bavaria shows no Omicron transmission before the end of November 2021.
      aug:
        au:
          Flechsler, Jennifer
          Eberle, Ute
          Dangel, Alexandra
          Hepner, Sabrina
          Wimmer, Clara
          Lutmayr, Johannes
          Konrad, Regina
          Berger, Carola
          Weise, Laura
          Sprenger, Annika
          Zeitler, Jörg
          Paravinja, Natali
          Angermeier, Hildegard
          Githure, George
          Schmidt, Sandra
          Treis, Bianca
          Okeyo, Mercy
          Liebl, Bernhard
          Ackermann, Nikolaus
          Sing, Andreas
        affil: Department of Public Health Microbiology, Bavarian Health and Food Safety Authority (LGL), Veterinärstraße 2, 85764, Oberschleißheim, Germany
      sug:
        subj:
          COVID-19 Diagnosis
          Disease Transmission Analysis
          Disease Surveillance
          Human
          Reverse Transcriptase Polymerase Chain Reaction Utilization
          Germany
          RNA Analysis
          Data Analysis Software
      ab: Background: Five SARS-CoV-2 variants are currently considered as variants of concern (VOC). Omicron was declared a VOC at the end of November 2021. Based on different diagnostic methods, the occurrence of Omicron was reported by 52 countries worldwide on December 7 2021. First notified by South Africa with alarming reports on increasing infection rates, this new variant was soon suspected to replace the currently pre-dominating Delta variant leading to further infection waves worldwide. Methods: Using VOC PCR screening and Next Generation Sequencing (NGS) analysis of selected samples, we investigated the circulation of Omicron in the German federal state Bavaria. For this, we analyzed SARS-CoV-2 surveillance data from our laboratory generated from calendar week (CW) 01 to 49/2021. Results: So far, we have detected 69 Omicron cases in our laboratory from CW 47–49/2021 using RT-qPCR followed by melting curve analysis. The first 16 cases were analyzed by NGS and all were confirmed as Omicron. Conclusion: Our data strongly support no circulation of the new Omicron variant before CW 47/2021.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N