ALK-Fusion Transcripts Can Be Detected in Extracellular Vesicles (EVs) from Nonsmall Cell Lung Cancer Cell Lines and Patient Plasma: Toward EV-Based Noninvasive Testing.

BACKGROUND: ALK rearrangements are present in 5% of nonsmall cell lung cancer (NSCLC) tumors and identify patients who can benefit from ALK inhibitors. ALK fusions testing using liquid biopsies, although challenging, can expand the therapeutic options for ALK-positive NSCLC patients considerably. RN...

Descripción completa

Detalles Bibliográficos

Publicado en:	Clinical Chemistry Vol. 68; no. 5; pp. 668 - 680
Autores principales:	Sánchez-Herrero, Estela, Campos-Silva, Carmen, Cáceres-Martell, Yaiza, Robado de Lope, Lucía, Sanz-Moreno, Sandra, Serna-Blasco, Roberto, Rodríguez-Festa, Alejandro, Ares Trotta, Dunixe, Martín-Acosta, Paloma, Patiño, Cristina, Coronado, María José, Beneitez, Alexandra, Jara, Ricardo, Lago-Baameiro, Nerea, Camino, Tamara, Cruz-Bermúdez, Alberto, Pardo, María, González-Rumayor, Víctor, Valés-Gómez, Mar, Provencio, Mariano
Formato:	Journal Article
Publicado:	Oxford University Press / USA May2022
Acceso en línea:	Ver este registro en EBSCOhost