Automating Scoliosis Measurements in Radiographic Studies with Machine Learning: Comparing Artificial Intelligence and Clinical Reports.

Scoliosis is a condition of abnormal lateral spinal curvature affecting an estimated 2 to 3% of the US population, or seven million people. The Cobb angle is the standard measurement of spinal curvature in scoliosis but is known to have high interobserver and intraobserver variability. Thus, the obj...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 3; pp. 524 - 534
Autores principales: Ha, Audrey Y., Do, Bao H., Bartret, Adam L., Fang, Charles X., Hsiao, Albert, Lutz, Amelie M., Banerjee, Imon, Riley, Geoffrey M., Rubin, Daniel L., Stevens, Kathryn J., Wang, Erin, Wang, Shannon, Beaulieu, Christopher F., Hurt, Brian
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Jun2022
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Automating Scoliosis Measurements in Radiographic Studies with Machine Learning: Comparing Artificial Intelligence and Clinical Reports.
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          Ha, Audrey Y.
          Do, Bao H.
          Bartret, Adam L.
          Fang, Charles X.
          Hsiao, Albert
          Lutz, Amelie M.
          Banerjee, Imon
          Riley, Geoffrey M.
          Rubin, Daniel L.
          Stevens, Kathryn J.
          Wang, Erin
          Wang, Shannon
          Beaulieu, Christopher F.
          Hurt, Brian
        affil: Department of Radiology, Stanford University, 300 Pasteur Drive, 94305, Stanford, CA, USA
      sug:
        subj:
          Machine Learning
          Scoliosis Radiography
          Automation
          Medical Practice
          Human
          Artificial Intelligence
          Retrospective Design
          Descriptive Statistics
          Radiography
          Tertiary Health Care
          Confidence Intervals
      ab: Scoliosis is a condition of abnormal lateral spinal curvature affecting an estimated 2 to 3% of the US population, or seven million people. The Cobb angle is the standard measurement of spinal curvature in scoliosis but is known to have high interobserver and intraobserver variability. Thus, the objective of this study was to build and validate a system for automatic quantitative evaluation of the Cobb angle and to compare AI generated and human reports in the clinical setting. After IRB was obtained, we retrospectively collected 2150 frontal view scoliosis radiographs at a tertiary referral center (January 1, 2019, to January 1, 2021, ≥ 16 years old, no hardware). The dataset was partitioned into 1505 train (70%), 215 validation (10%), and 430 test images (20%). All thoracic and lumbar vertebral bodies were segmented with bounding boxes, generating approximately 36,550 object annotations that were used to train a Faster R-CNN Resnet-101 object detection model. A controller algorithm was written to localize vertebral centroid coordinates and derive the Cobb properties (angle and endplate) of dominant and secondary curves. AI-derived Cobb angle measurements were compared to the clinical report measurements, and the Spearman rank-order demonstrated significant correlation (0.89, p < 0.001). Mean difference between AI and clinical report angle measurements was 7.34° (95% CI: 5.90–8.78°), which is similar to published literature (up to 10°). We demonstrate the feasibility of an AI system to automate measurement of level-by-level spinal angulation with performance comparable to radiologists.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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