Optimizing a Deep Residual Neural Network with Genetic Algorithm for Acute Lymphoblastic Leukemia Classification.

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer worldwide, and it is characterized by the production of immature malignant cells in the bone marrow. Computer vision techniques provide automated analysis that can help specialists diagnose this disease. Microscopy image analysis...

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Publicado en:Journal of Digital Imaging Vol. 35; no. 3; pp. 623 - 638
Autores principales: Rodrigues, Larissa Ferreira, Backes, André Ricardo, Travençolo, Bruno Augusto Nassif, de Oliveira, Gina Maira Barbosa
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jun2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00600-3
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        atl: Optimizing a Deep Residual Neural Network with Genetic Algorithm for Acute Lymphoblastic Leukemia Classification.
      aug:
        au:
          Rodrigues, Larissa Ferreira
          Backes, André Ricardo
          Travençolo, Bruno Augusto Nassif
          de Oliveira, Gina Maira Barbosa
        affil: Faculty of Computing (FACOM), Federal University of Uberlândia (UFU), Uberlândia, MG, Brazil
      sug:
        subj:
          Neural Networks (Computer)
          Genetic Algorithms
          Leukemia, Lymphocytic, Acute Classification
          Human
          Probability
          Bone Marrow
          Prediction Models
          Descriptive Statistics
          Leukemia Diagnosis
      ab: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer worldwide, and it is characterized by the production of immature malignant cells in the bone marrow. Computer vision techniques provide automated analysis that can help specialists diagnose this disease. Microscopy image analysis is the most economical method for the initial screening of patients with ALL, but this task is subjective and time-consuming. In this study, we propose a hybrid model using a genetic algorithm (GA) and a residual convolutional neural network (CNN), ResNet-50V2, to predict ALL using microscopy images available in ALL-IDB dataset. However, accurate prediction requires suitable hyperparameters setup, and tuning these values manually still poses challenges. Hence, this paper uses GA to find the best hyperparameters that lead to the highest accuracy rate in the models. Also, we compare the performance of GA hyperparameter optimization with Random Search and Bayesian optimization methods. The results show that GA optimization improves the accuracy of the classifier, obtaining 98.46% in terms of accuracy. Additionally, our approach sheds new perspectives on identifying leukemia based on computer vision strategies, which could be an alternative for applications in a real-world scenario.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
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      ougenre: Article
    language: English
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