Non-Mutated Nucleophosmin 1 Is Recognized by the CD8+ T Lymphocytes of an AML Patient after the Transplantation of Hematopoietic Stem Cells from an HLA-Haploidentical Donor.

Simple Summary: Our study describes an AML patient whose leukemia cells carried the NPM1c+ mutation, and who was the recipient of allogeneic HSCT from a haploidentical donor. The patient raised a robust allorestricted CD8+ T cell response directed against the NPM1wt protein. Favourably, the response...

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Publicado en:Current Oncology Vol. 29; no. 5; pp. 2928 - 2935
Autores principales: Nemeckova, Sarka, Alexova-Zurkova, Kamila, Hainz, Petr, Krystofova, Jitka, Mackova, Jana, Roubalova, Katerina, Stastna-Markova, Marketa, Vrana, Milena, Vydra, Jan
Formato: Journal Article
Publicado: MDPI May2022
Acceso en línea:Ver este registro en EBSCOhost