Burden of Antibiotic Resistance at Wolaita Sodo University Comprehensive Specialized Hospital.

Background. Antibiotic resistance is a serious threat to the human population everywhere. However, less attention is given to its concern in sub-Saharan Africa including Ethiopia. There is an information gap concerning antibiotic resistance and its pattern in Wolaita Sodo University Teaching Referra...

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Publicado en:BioMed Research International pp. 1 - 11
Autores principales: Ageru, Temesgen Anjulo, Seid, Habtamu, Abiso, Temesgen Lera, Kumalo, Abera, Sidamo, Temesgen, Balcha, Tamrat
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/2/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/2/2022
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2022/7272024
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        atl: Burden of Antibiotic Resistance at Wolaita Sodo University Comprehensive Specialized Hospital.
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          Ageru, Temesgen Anjulo
          Seid, Habtamu
          Abiso, Temesgen Lera
          Kumalo, Abera
          Sidamo, Temesgen
          Balcha, Tamrat
        affil: Department of Medical Laboratory Services, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita, P.O. Box 138, Ethiopia
      sug:
        subj:
          Bacterial Infections Drug Therapy
          Antibiotics Therapeutic Use
          Drug Resistance, Microbial Evaluation
          Academic Medical Centers
          Human
          Ethiopia
          Retrospective Design
          Record Review
          Microbial Culture and Sensitivity Tests
          Data Analysis Software
          Male
          Female
          Gram-Positive Bacteria
          Gram-Negative Bacteria
          Staphylococcus Aureus
          Escherichia Coli
          Descriptive Statistics
          Male
          Female
      ab: Background. Antibiotic resistance is a serious threat to the human population everywhere. However, less attention is given to its concern in sub-Saharan Africa including Ethiopia. There is an information gap concerning antibiotic resistance and its pattern in Wolaita Sodo University Teaching Referral Hospital. This study is aimed at investigating the prevalence of antimicrobial resistance in the study area. Methods. Five-year retrospective data of cultures and records of 581 patients were utilized to analyze the pattern of antibiotic resistance. The statistical software including SPSS version 25 and Microsoft excel 2013 were used. Laboratory records with incompletely registered age, sex, culture isolation, or drug susceptibility test data were excluded. Results. Out of the total of 581 samples extracted from the microbiology laboratory, 237 (40.8%) samples were culture positive for bacteria. From positive culture growth, 165 (69.6%) were gram-positive bacteria whereas 72 (30.4%) were gram negative. Staphylococcus aureus was the most prevalent isolate among gram-positive isolates as Escherichia coli was for gram-negative isolates. Overall antibiotic resistance of gram-positive isolates was 57.2% whereas that of gram-negative bacteria was 58.8%.Conclusion. S. aureus and E. coli were found to be the most prevalent pathogenic isolates among gram-positive and gram-negative bacteria, respectively. Most of the isolated pathogens showed high resistance towards the commonly prescribed antibiotic agents. The overall antibiotic resistance in this study was 57.7%, and the overall MDR prevalence was 72.2%.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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