The association between undiagnosed diabetes and cognitive function: findings from the China health and retirement longitudinal study.

Background: The cognitive function of people with diabetes has gained an increasing interest in recent years, and this study focuses on exploring the relationship between undiagnosed diabetes and cognitive function among the middle-aged and elderly people in China. Methods: The data came from the Ch...

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Publicado en:BMC Endocrine Disorders Vol. 22; no. 1; pp. 1 - 11
Autores principales: Yang, Jiafei, Xu, Haiming, Li, Jiangping, Zhao, Yu, Guan, Suzhen, Fu, Youjuan, Bao, Rui, Liu, Zhihong
Formato: research tables/charts Journal Article
Publicado: BioMed Central 6/4/2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/4/2022
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      pub: BioMed Central
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        10.1186/s12902-022-01055-x
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        atl: The association between undiagnosed diabetes and cognitive function: findings from the China health and retirement longitudinal study.
      aug:
        au:
          Yang, Jiafei
          Xu, Haiming
          Li, Jiangping
          Zhao, Yu
          Guan, Suzhen
          Fu, Youjuan
          Bao, Rui
          Liu, Zhihong
        affil: Department of Epidemiology and Health Statistics, School of Public Health and Management, Ningxia Medical University, 750004, Yinchuan, Ningxia Hui Autonomous Region, China
      sug:
        subj:
          Diabetes Mellitus China
          Undiagnosed Diseases Complications
          Cognition In Old Age
          Cognition Disorders Risk Factors
          Human
          China
          Prospective Studies
          Middle Age
          Aged
          Aged, 80 and Over
          Executive Function
          Episodic Memory
          Multiple Linear Regression
          Diabetic Patients
          Retirement
          Risk Assessment
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
      ab: Background: The cognitive function of people with diabetes has gained an increasing interest in recent years, and this study focuses on exploring the relationship between undiagnosed diabetes and cognitive function among the middle-aged and elderly people in China. Methods: The data came from the China Health and Retirement Longitudinal Study (CHARLS) which was conducted between July and October 2015. 9855 subjects were enrolled in the study. Executive function and episodic memory were used to assess cognitive function. The subjects were divided into three groups: no diabetes, diagnosed diabetes, and undiagnosed diabetes, and weighted multiple linear regression models were established to evaluate the association of undiagnosed diabetes with cognitive function. Results: After controlling for covariates, undiagnosed diabetes was statistically associated with executive function (β = −0.215, P < 0.01). In the age group of ≥65 years, undiagnosed diabetes was statistically associated with executive function (β = −0.358, P < 0.01) and episodic memory (β = −0.356, P < 0.01). When adjusting for confounders, no statistically significant associations were found between diagnosed diabetes and cognitive function except in 45-54 age group (β = 0.374, P < 0.05). Conclusions: The cross-sectional study suggested that undiagnosed diabetes was linked to poor cognitive function, especially in the elderly population. Timely diagnosis and active treatment of diabetes are important to reduce the occurrence of cognitive impairment. Further prospective cohort studies are required to articulate the association between undiagnosed diabetes and cognitive function.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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