High-Risk Polymorphisms Associated with the Molecular Function of Human HMGCR Gene Infer the Inhibition of Cholesterol Biosynthesis.

HMG-CoA reductase or HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) is a rate-limiting enzyme involved in cholesterol biosynthesis. HMGCR plays an important role in the possible occurrence of hypercholesterolemia leading to atherosclerosis and coronary heart disease. This enzyme is a major target...

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Bibliographic Details

Published in:	BioMed Research International pp. 1 - 18
Main Authors:	Das, Keshob Chandra, Hossain, Mohammad Uzzal, Moniruzzaman, Md, Salimullah, Md, Akhteruzzaman, Sharif
Format:	pictorial research tables/charts Journal Article
Published:	Wiley-Blackwell 6/6/2022
Online Access:	View this record in EBSCOhost