Impact of body mass index on cryoablation of atrial fibrillation: Patient characteristics, procedural data, and long‐term outcomes.
Introduction: Ablation of atrial fibrillation in the context of obesity can be challenging. We sought to evaluate the role of cryoballoon pulmonary vein isolation (CB‐PVI) in obese patients with symptomatic atrial fibrillation (AF). Methods: Patients with a BMI ≥ 25 kg/m2 and symptomatic AF who unde...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 33; no. 6; pp. 1106 - 1116 |
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| Autores principales: | , , , , , , , , |
| Formato: | diagnostic images research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Jun2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157331163&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157331163 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Jun2022 vid: 33 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 157331163 156186180 157331163 157331163 10.1111/jce.15478 157331163 ppf: 1106 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Impact of body mass index on cryoablation of atrial fibrillation: Patient characteristics, procedural data, and long‐term outcomes. aug: au: Urbanek, Lukas Bordignon, Stefano Chen, Shaojie Bologna, Fabrizio Tohoku, Shota Dincher, Matthias Schulte‐Hahn, Britta Schmidt, Boris Chun, Kyoung‐Ryul Julian affil: Cardioangiologisches Centrum Bethanien, Agaplesion Markus‐Krankenhaus, Frankfurt am Main, Germany sug: subj: Atrial Fibrillation Surgery Cryosurgery Methods Cryosurgery Adverse Effects Obesity Body Mass Index Treatment Outcomes Evaluation Human Retrospective Design Record Review Surgical Patients Psychosocial Factors Comparative Studies Male Female Middle Age Aged Fluoroscopy Radiation Dosage Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Introduction: Ablation of atrial fibrillation in the context of obesity can be challenging. We sought to evaluate the role of cryoballoon pulmonary vein isolation (CB‐PVI) in obese patients with symptomatic atrial fibrillation (AF). Methods: Patients with a BMI ≥ 25 kg/m2 and symptomatic AF who underwent CB‐PVI were retrospectively enrolled. Three groups were defined (G1: BMI of 25–29 kg/m2; G2: BMI of 30–34 kg/m2; G3: BMI ≥ 35 kg/m2). Results: 600 patients were included (59% male; 66 ± 11 years old); 337, 149, and 114 were assigned to G1, G2, and G3, respectively. Acute procedural success was recorded in 99.7% of patients. Procedural and fluoroscopy time were comparable but the radiation dose was significantly higher in G3. Procedural complications were 3% in G1, 5.4% in G2, and 8.8% in G3 (p =.01). The overall freedom from AF after 1‐year was 77%. G3 had a significantly worse 1‐year success rate compared to G1 and G2 (G3: 66.5% vs. G1: 78.4%; p =.015 and vs. G2: 82.5%; p =.008) with reduced 1‐year success in paroxysmal AF (G1: 84.0%; G2: 86.3%; and G3: 69.6%) but not in persistent AF (G1: 68.7%; G2: 77.4%; and G3: 62.1%). G3 showed similar success rates irrespective of AF form (PAF: 69.6% vs. persAF 62.1%; p =.501). Conclusion: Cryoballoon ablation in obese patients can be effective with an acceptable safety profile, 77% of patients were in stable SR at 1 year. Severe obese patients (BMI ≥ 35) showed reduced procedural safety and 1‐year success rate. In association with life style modification, CB ablation may represent a strategy to enhance rhythm control in the context of obesity. pubtype: Academic Journal doctype: diagnostic images research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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