Today's Mistakes and Tomorrow's Wisdom... In Barrett's Surveillance.
Background: Barrett's esophagus (BE) is the only known precursor lesion of esophageal adenocarcinoma, a malignancy with increasing incidence and poor survival rates. To reduce mortality, regular endoscopic surveillance of BE patients is recommended to detect neoplasia in an (endoscopically) curable...
| Publicado en: | Visceral Medicine Vol. 38; no. 3; pp. 168 - 173 |
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| Autores principales: | , , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Karger AG
2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157360878&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157360878 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 22974725 KAU3 jtl: Visceral Medicine issn: 22974725 maglogo: N pubinfo: dt: 2022 vid: 38 iid: 3 pid: 2485 pub: Karger AG artinfo: ui: 157360878 155540391 157360878 157360878 10.1159/000522376 157360878 ppf: 168 ppct: 5 formats: tig: atl: Today's Mistakes and Tomorrow's Wisdom... In Barrett's Surveillance. aug: au: Zellenrath, Pauline A. Roumans, Carlijn A.M. Spaander, Manon C.W. affil: Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands sug: subj: Barrett Esophagus Disease Surveillance Costs and Cost Analysis Economic Aspects of Illness Risk Assessment Esophageal Neoplasms Adenocarcinoma Practice Guidelines ab: Background: Barrett's esophagus (BE) is the only known precursor lesion of esophageal adenocarcinoma, a malignancy with increasing incidence and poor survival rates. To reduce mortality, regular endoscopic surveillance of BE patients is recommended to detect neoplasia in an (endoscopically) curable stage. In this review, we aim to provide an overview of current BE surveillance strategies, its pitfalls, and potential future directions to optimize BE surveillance. Summary: Several societal guidelines provide surveillance strategies. However, when practicing those endoscopies multiple drawbacks are encountered. Important challenges are time-consuming biopsy protocols with low adherence rates, biopsy sampling error, interobserver variability in endoscopic detection of lesions, and interobserver variability in diagnosis of dysplasia. Furthermore, the overall efficacy and cost-effectiveness of surveillance are questioned. Using novel techniques, such as artificial intelligence and personalized surveillance intervals, can help to overcome these obstacles. Key Messages: Currently, there is room for improvement in BE surveillance. Better risk-stratification is expected to reduce both patient and healthcare burdens. Personalized and dynamic surveillance intervals accompanied by novel techniques in detection and histopathological assessment of dysplasia may be tools for a change in the right direction. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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