Design of New Potent and Selective Thiophene-Based K V 1.3 Inhibitors and Their Potential for Anticancer Activity.

Simple Summary: In this article, we describe the discovery of a new class of potent and selective thiophene-based inhibitors of the voltage-gated potassium channel KV1.3 and their potential to induce apoptosis and inhibit proliferation. The KV1.3 channel has only recently emerged as a molecular targ...

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Bibliographic Details

Published in:	Cancers Vol. 14; no. 11; pp. 2595 - 2615
Main Authors:	Gubič, Špela, Hendrickx, Louise Antonia, Shi, Xiaoyi, Toplak, Žan, Možina, Štefan, Theemsche, Kenny M. Van, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Labro, Alain J., Pardo, Luis A., Tytgat, Jan, Tomašič, Tihomir, Mašič, Lucija Peterlin
Format:	pictorial research tables/charts Journal Article
Published:	MDPI Jun2022
Online Access:	View this record in EBSCOhost