Relationship between door-to-embolization time and clinical outcomes after transarterial embolization in trauma patients with complex pelvic fracture.
Background: While transarterial embolization (TAE) is an effective way to control arterial bleeding associated with pelvic fracture, the clinical outcomes according to door-to-embolization (DTE) time are unclear. This study investigated how DTE time affects outcomes in patients with severe pelvic fr...
| Published in: | European Journal of Trauma & Emergency Surgery Vol. 48; no. 3; pp. 1929 - 1939 |
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| Main Authors: | , , , , , , , , , , , |
| Format: | algorithm research tables/charts Journal Article |
| Published: |
Springer Nature
Jun2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157411432&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157411432 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18639933 3C05 jtl: European Journal of Trauma & Emergency Surgery issn: 18639933 maglogo: N pubinfo: dt: Jun2022 vid: 48 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 157411432 148417978 157411432 157411432 10.1007/s00068-021-01601-7 157411432 ppf: 1929 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Relationship between door-to-embolization time and clinical outcomes after transarterial embolization in trauma patients with complex pelvic fracture. aug: au: Kim, Hohyun Jeon, Chang Ho Kim, Jae Hun Kwon, Hoon Kim, Chang Won Kim, Gil Hwan Lee, Chan Kyu Lee, Sang Bong Jang, Jae Hoon Kim, Seon Hee Park, Chan Yong Yeom, Seok Ran affil: Department of Trauma Surgery and Surgical Critical Care, Pusan National University Hospital, 179 Gudeok-Ro, Seo-Gu, 49241, Busan, Korea sug: subj: Pelvic Fractures Surgery Multiple Trauma Surgery Pelvic Fractures Prognosis Multiple Trauma Prognosis Embolization, Therapeutic Treatment Delay Treatment Outcomes Evaluation Time Factors Human Emergency Patients Retrospective Design Record Review Surgical Patients Multiple Logistic Regression Multiple Linear Regression Cox Proportional Hazards Model Pelvic Fractures Mortality Descriptive Statistics Risk Assessment Odds Ratio Confidence Intervals Survival Analysis ab: Background: While transarterial embolization (TAE) is an effective way to control arterial bleeding associated with pelvic fracture, the clinical outcomes according to door-to-embolization (DTE) time are unclear. This study investigated how DTE time affects outcomes in patients with severe pelvic fracture. Methods: Using a trauma database between November 1, 2015 and December 31, 2019, trauma patients undergoing TAE were retrospectively reviewed. The final study population included 192 patients treated with TAE. The relationships between DTE time and patients' outcomes were evaluated. Multiple binomial logistic regression analyses, multiple linear regression analyses, and Cox hazard proportional regression analyses were performed to estimate the impacts of DTE time on clinical outcomes. Results: The median DTE time was 150 min (interquartile range, 121–184). The mortality rates in the first 24 h and overall were 3.7% and 14.6%, respectively. DTE time served as an independent risk factor for mortality in the first 24 h (adjusted odds ratio = 2.00, 95% confidence interval [CI] = 1.20–3.34, p = 0.008). In Cox proportional hazards regression analyses, the adjusted hazard ratio of DTE time for mortality at 28 days was 1.24 (95% CI = 1.04–1.47, p = 0.014). In addition, there was a positive relationship between DTE time and requirement for packed red blood cell transfusion during the initial 24 h and a negative relationship between DTE time and ICU-free days to day 28. Conclusion: Shorter DTE time was associated with better survival in the first 24 h, as well as other clinical outcomes, in patients with complex pelvic fracture who underwent TAE. Efforts to minimize DTE time are recommended to improve the clinical outcomes in patients with pelvic fracture treated with TAE. pubtype: Academic Journal doctype: algorithm research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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