Incidence, risk factors and clinical course of pyogenic spondylodiscitis patients with pulmonary embolism.
Purpose: In patients with pyogenic spondylodiscitis, surgery is considered the treatment of choice to conduct proper debridement, stabilise the spine and avoid extended bed rest, which in turn is a risk factor for complications such as deep vein thrombosis and pulmonary embolism. Methods: We conduct...
| Publicado en: | European Journal of Trauma & Emergency Surgery Vol. 48; no. 3; pp. 2229 - 2237 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=157411482&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 157411482 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18639933 3C05 jtl: European Journal of Trauma & Emergency Surgery issn: 18639933 maglogo: N pubinfo: dt: Jun2022 vid: 48 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 157411482 152223467 157411482 157411482 10.1007/s00068-021-01776-z 157411482 ppf: 2229 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Incidence, risk factors and clinical course of pyogenic spondylodiscitis patients with pulmonary embolism. aug: au: Dubinski, Daniel Won, Sae-Yeon Keil, Fee Behmanesh, Bedjan Dosch, Max Baumgarten, Peter Bernstock, Joshua D. Seifert, Volker Freiman, Thomas M. Gessler, Florian affil: Department of Neurosurgery, University Hospital, Goethe University, Schleusenweg 2-16, 60598, Frankfurt, Germany sug: subj: Pulmonary Embolism Epidemiology Spinal Diseases Surgery Discitis Complications Pulmonary Embolism Risk Factors Risk Assessment Human Retrospective Design Venous Thrombosis Complications Resuscitation Adverse Effects Incidence Hospital Mortality Comorbidity Adverse Effects Body Mass Index Smoking Complications Coronary Disease Complications Sex Factors Anticoagulants Adverse Effects Germany ab: Purpose: In patients with pyogenic spondylodiscitis, surgery is considered the treatment of choice to conduct proper debridement, stabilise the spine and avoid extended bed rest, which in turn is a risk factor for complications such as deep vein thrombosis and pulmonary embolism. Methods: We conducted a retrospective clinical study with analysis of a group of 99 patients who had undergone treatment for pyogenic discitis at our institution between June 2012 and August 2017. Included parameters were age, sex, disease pattern, the presence of deep vein thrombosis, resuscitation, in-hospital mortality, present anticoagulation, preexisting comorbidities, tobacco abuse, body mass index, microbiological germ detection and laboratory results. Results: Among the analysed cohort, 12% of the treated patients for pyogenic spondylodiscitis suffered from a radiologically confirmed pulmonary embolism. Coronary heart disease (p < 0.01), female sex (p < 0.01), anticoagulation at admission (p < 0.01) and non-O blood type (p < 0.001) were associated with development of pulmonary embolism. Pulmonary embolism was significantly associated with resuscitation (p < 0.005) and deep vein thrombosis (p < 0.001). Neurosurgery was not associated with increased risk for pulmonary embolism compared to conservative-treated patients (p > 0.05). Conclusion: Surgery for pyogenic spondylodiscitis was not associated with an elevated risk of pulmonary embolism in our analysis. However, we describe several risk factors for pulmonary embolism in this vulnerable cohort. Prospective studies are necessary to improve prevention and postoperative management in patients with pyogenic spondylodiscitis. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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