The pediatric urobiome in genitourinary conditions: a narrative review.

The microbial ecosystem within the bladder that can be measured within the urine, or urobiome, is an emerging field of study with little published data regarding children. However, investigations into urobiome research have the potential to significantly impact the understanding of the pathophysiolo...

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Detalles Bibliográficos
Publicado en:Pediatric Nephrology Vol. 37; no. 7; pp. 1443 - 1453
Autores principales: Cole, Elisabeth, Shaikh, Nader, Forster, Catherine S.
Formato: pictorial review tables/charts Journal Article
Publicado: Springer Nature Jul2022
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The microbial ecosystem within the bladder that can be measured within the urine, or urobiome, is an emerging field of study with little published data regarding children. However, investigations into urobiome research have the potential to significantly impact the understanding of the pathophysiology of genitourinary conditions, as well as potentially identify novel therapeutics. Therefore, both researchers and clinicians should be aware of pediatric urobiome research. The purpose of this review is to highlight the literature around urobiome research in urinary tract infections, nephrolithiasis, and neurogenic bladder; comment on pediatric-specific considerations when reading and interpreting the urobiome literature; and to identify new potential areas of research.