Relationship between high‐risk alcohol consumption and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) seroconversion: a prospective sero‐epidemiological cohort study among American college students.

Aims: To estimate the associations between high‐risk alcohol consumption and (1) severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) seroconversion, (2) self‐reported new SARS‐CoV‐2 infection and (3) symptomatic COVID‐19. Design Prospective cohort study. Setting: Indiana University Blooming...

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Publicado en:Addiction Vol. 117; no. 7; pp. 1908 - 1920
Autores principales: Kianersi, Sina, Ludema, Christina, Macy, Jonathan T., Chen, Chen, Rosenberg, Molly
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jul2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2022
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Relationship between high‐risk alcohol consumption and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) seroconversion: a prospective sero‐epidemiological cohort study among American college students.
      aug:
        au:
          Kianersi, Sina
          Ludema, Christina
          Macy, Jonathan T.
          Chen, Chen
          Rosenberg, Molly
        affil: Department of Epidemiology and Biostatistics, Indiana University School of Public Health‐Bloomington, Bloomington IN,, USA
      sug:
        subj:
          Alcohol Drinking in College
          Alcohol Abuse Indiana
          COVID-19 Risk Factors
          Seroconversion
          Risk Assessment
          Human
          Prospective Studies
          Epidemiological Research
          Students, College
          Students, Undergraduate
          Questionnaires
          Self Report
          Descriptive Statistics
          Confidence Intervals
          Prevalence
          Dose-Response Relationship
          Female
          Male
          Adolescence
          Young Adult
          Indiana
          Adolescent: 13-18 years
          Female
          Male
      ab: Aims: To estimate the associations between high‐risk alcohol consumption and (1) severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) seroconversion, (2) self‐reported new SARS‐CoV‐2 infection and (3) symptomatic COVID‐19. Design Prospective cohort study. Setting: Indiana University Bloomington (IUB), IN, USA. Participants: A total of 1027 IUB undergraduate students (64% female), aged 18 years or older, residing in Monroe County, Indiana, seronegative for SARS‐CoV‐2 at study baseline. Measurements Primary exposure was high‐risk alcohol consumption measured with an Alcohol Use Disorders Identification Test (AUDIT) questionnaire score of 8 or more. Primary outcome was SARS‐CoV‐2 seroconversion since baseline, assessed with two SARS‐CoV‐2 antibody tests, at baseline (September 2020) and end‐line (November 2020). Secondary outcomes were (a) self‐reported new SARS‐CoV‐2 infection at the study end‐line and (b) self‐reported symptomatic COVID‐19 at baseline. Findings Prevalence of high‐risk alcohol consumption was 32 %. In models adjusted for demographics, students with high‐risk alcohol consumption status had 2.44 [95% confidence interval (CI) = 1.35, 4.25] times the risk of SARS‐CoV‐2 seroconversion and 1.84 (95% CI = 1.04, 3.28) times the risk of self‐reporting a positive SARS‐CoV‐2 infection, compared with students with no such risk. We did not identify any association between high‐risk alcohol consumption and symptomatic COVID‐19 (prevalence ratio = 1.17, 95% CI = 0.93, 1.47). Findings from sensitivity analyses corroborated these results and suggested potential for a dose–response relationship. Conclusions: Among American college students, high‐risk alcohol consumption appears to be associated with higher risk for severe acute respiratory syndrome coronavirus 2 seroconversion/infection.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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