MicroPET imaging of bacterial infection with nitroreductase-specific responsive 18F-labelled nitrogen mustard analogues.

Purpose: Bacterial infection and antibiotic resistance are serious threats to human health. This study aimed to develop two novel radiotracers, 18F-NTRP and 18F-NCRP, that possess a specific nitroreductase (NTR) response to image deep-seated bacterial infections using positron emission tomography (P...

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Detalles Bibliográficos
Publicado en:European Journal of Nuclear Medicine & Molecular Imaging Vol. 49; no. 8; pp. 2645 - 2655
Autores principales: Huang, Lumei, Fang, Jianyang, Hong, Shouqiang, Liu, Huanhuan, Zhu, Haotian, Feng, Lixia, Zhuang, Rongqiang, Zhao, Xilin, Guo, Zhide, Zhang, Xianzhong
Formato: Journal Article
Publicado: Springer Nature Jul2022
Acceso en línea:Ver este registro en EBSCOhost