A prospective single centre case series on the use of epidermal grafts and adjunct technologies to facilitate wound healing in a vascular surgical patient population.

Epidermal grafting (EG) using a novel epidermal harvesting system (the CELLUTOME™ System) offers an alternative method to classic surgical approaches of assisted wound closure. Use of this device requires minimal training, leaves a nominal donor site injury, and may be employed in non-operating thea...

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Publicado en:Wound Practice & Research Vol. 30; no. 2; pp. 99 - 108
Autores principales: Guerriero, Frank P., Delaney, Christopher L.
Formato: case study pictorial research tables/charts Journal Article
Publicado: Cambridge Publishing Jun2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2022
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      pub: Cambridge Publishing
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        10.33235/wpr.30.2.99-107
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        atl: A prospective single centre case series on the use of epidermal grafts and adjunct technologies to facilitate wound healing in a vascular surgical patient population.
      aug:
        au:
          Guerriero, Frank P.
          Delaney, Christopher L.
        affil: Flinders University, SA, Australia
      sug:
        subj:
          Epidermis Transplantation
          Skin Transplantation Utilization
          Wound Care Methods
          Tissue and Organ Harvesting Equipment and Supplies
          Wound Healing
          Vascular Surgery
          Surgical Patients
          Human
          Prospective Studies
          Tertiary Health Care South Australia
          Hospitals, Urban South Australia
          South Australia
          Male
          Female
          Aged
          Middle Age
          Aged, 80 and Over
          Lower Extremity Pathology
          Peripheral Vascular Diseases Complications
          Venous Insufficiency Complications
          Diabetic Neuropathies Complications
          Ischemia Complications
          Treatment Outcomes
          Biodegradable Materials
          Technology, Medical
          Aged: 65+ years
          Middle Aged: 45-64 years
          Aged, 80 & over
          Male
          Female
      ab: Epidermal grafting (EG) using a novel epidermal harvesting system (the CELLUTOME™ System) offers an alternative method to classic surgical approaches of assisted wound closure. Use of this device requires minimal training, leaves a nominal donor site injury, and may be employed in non-operating theatre environments, lending to consideration for use in a high-risk vascular surgical cohort. This single centre series observed the application of EG to lower limb wounds in vascular surgical patients with aetiological barriers to wound healing, including peripheral arterial disease (PAD), venous insufficiency and diabetic neuro-ischaemia. Complete wound healing was established as the primary outcome measure, with time to 100% epithelialisation as a secondary outcome measure. Ten consecutive patients underwent EG via the CELLUTOME™ Epidermal Harvesting System for treatment of wounds related to a variety of vascular surgical aetiologies. Complete wound healing was observed in seven out of ten patients, significant wound surface area reduction was seen in one patient, with the remaining two patients failing to respond, requiring further surgery to facilitate wound healing. These results suggest that EG via the CELLUTOME™ System offers a viable option for assisted wound closure of wounded vascular surgical patients in whom avoidance of general anaesthesia may be desirable.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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